Results 141 to 150 of about 728,973 (290)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Forum: Qualitative Social Research, 2013 In this book the epistemologist of the social sciences Ulises TOLEDO NICKELS develops a reconstruction of a number of theoretical, epistemological, and methodological reflections and of the findings of empirical research that, during the 20th century ...
Fernando Farías Olavarría
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The Pessimistic Induction: A Bad Argument Gone Too Far [PDF]
, 2012 In this paper, I consider the pessimistic induction construed as a deductive argument (specifically, reductio ad absurdum) and as an inductive argument (specifically, inductive generalization).
Mizrahi, Moti
core
Christopher W. Tindale, Fallacies and Argument Appraisal [PDF]
Argumentation, 2008 openaire +2 more sources
Appraising EFL Students’ Syntactic Competency of Word Formation in Argumentative Writing
Jo-ELT (Journal of English Language Teaching) Fakultas Pendidikan Bahasa & Seni Prodi Pendidikan Bahasa Inggris IKIPEFL teaching participants must learn the uncommon language, so that teachers or educators need to discover several problems in conveying the material. This research investigated syntactic labels in recognizing word formation in simple sentences such as subject, verb/predicate, object, and adverb.
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2014 :Learning Biology through Argument-Driven Inquiry Strategies and Argumentation Skills ofStudent. Argumentation skills as a form of communication to externalise ideas through scientific discourseis a very important process in learning biology.
Hasnunidah, Neni
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source