Results 71 to 80 of about 17,062,176 (325)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Verbs, nouns and affixation [PDF]

, 2008
What explains the rich patterns of deverbal nominalization? Why do some nouns have argument structure, while others do not? We seek a solution in which properties of deverbal nouns are composed from properties of verbs, properties of nouns, and ...
Alexiadou, Artemis, Grimshaw, Jane
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

STRUKTUR ARGUMEN DALAM WACANA KARYA TULIS ILMIAH MAHASISWA

Litera, 2015
This study aims to describe argument structures based on types of complexity and conclusion drawing in students’ academic writing discourse. It employed the qualitative descriptive approach using the communication content analysis method.
Ardianto Ardianto
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Frá skiptisögn til ósamhverfrar aukafallssagnar. Um 'líka' í fornu máli

Orð og Tunga, 2020
In Modern Icelandic the verb líka ‘like’ occurs with a subject in the dative case and an object in the nominative case. It has been argued that this was also the case in Old Icelandic.
Einar Freyr Sigurðsson, Heimir van der Feest Viðarsson   +1 more
doaj   +1 more source

Numerical calculation of Bessel, Hankel and Airy functions

, 2011
The numerical evaluation of an individual Bessel or Hankel function of large order and large argument is a notoriously problematic issue in physics. Recurrence relations are inefficient when an individual function of high order and argument is to be ...
Abramowitz, Airy, Balogh, Baruth, Bickley, Caliceti, Cherry, Cherry, Cuyt, Debye, E. Lötstedt, Fabijonas, Gautschi, Gil, Gil, Grimshaw, Howls, Jackson, Jentschura, Jentschura, Jentschura, Langer, Langer, Langer, Lötstedt, Matviyenko, Miller, Mohr, Mohr, Mohr, Nicholson, Olver, Olver, Olver, Olver, Paris, Paris, Paris, Schulten, Shi, Smink, Temme, Temme, Temme, U.D. Jentschura, Vallée, Watson, Watson, Weniger, Weniger, Weniger, Wolfram   +51 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The Penn Treebank: Annotating Predicate Argument Structure

Human Language Technology - The Baltic Perspectiv, 1994
The Penn Treebank has recently implemented a new syntactic annotation scheme, designed to highlight aspects of predicate-argument structure. This paper discusses the implementation of crucial aspects of this new annotation scheme.
Mitchell P. Marcus, Grace Kim, Mary Ann Marcinkiewicz, R. MacIntyre, Ann Bies, Mark Ferguson, Karen Katz, Britta Schasberger   +7 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source