Results 51 to 60 of about 81,011 (298)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

How Edmodo as an Online Tool in EFL Writing Class can Increase Students’ Writing Ability

open access: yesRegister Journal, 2018
This paper reports the results of the investigation on the utilization of Edmodo as an online tool in EFL writing class to increase the students’ ability in producing an argumentative essay. Classroom Action Research was applied in the study.
M. Zaini Miftah
doaj   +1 more source

Esl Writing Variability: Writing Tasks, Gender And Proficiency Level [PDF]

open access: yes, 2007
Research focusing on L1 (native speakers of English) writers has shown that students tend to perform differently on different writing tasks. L1 students perform better on narrative and descriptive writing tasks than argumentative. In fact, some scholars
Rafik-Galea, S. (Shameem)   +1 more
core  

Activating argumentation schema to write argumentatively and tactfully

open access: yesActa Psychologica
To argue tactfully is a goal in argumentative writing, which entails balanced argumentation schema. Although computer-supported collaborative learning (CSCL) has been widely acknowledged as language learning mediation, especially in writing, few studies investigate its effectiveness in activating the balanced argumentation schema.
Donghong Liu, Qiong Gan, Hui Ma
openaire   +3 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

A case study of argumentation at undergraduate level in history [PDF]

open access: yes, 2009
This article examines two essays by undergraduate students in the first year of study in History at a university in the UK. It also draws on documentary evidence from the department in question and interviews with the students themselves to paint a ...
CJ Torgerson   +6 more
core   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A COLLABORATIVE WRITING TECHNIQUE TO IMPROVE STUDENTS’ SKILL IN WRITING ARGUMENTATIVE ESSAY (A Classroom Action Research at the Fourth Semeseter Students of English Education Department of IKIP PGRI Bojonegoro in the Academic Year of 2013/2014 [PDF]

open access: yes, 2016
: This research investigates whether Collaborative Writing Technique can improve students’ skill in writing argumentative essay and how class situation is when Collaborative Writing Technique is implemented.
Ghufron, M. Ali
core  

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

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