Results 91 to 100 of about 47,373 (236)

Evaluation of the Anticancer Effect of a Niosomal Suspension of Aripiprazole against the HT-29 Cell Line [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Cancer is one of the leading causes of death worldwide. One of the emerging approaches in therapeutic studies on various cancers is the use of non-specific drugs in cancer treatment.
hosein mahboudi, mohammad lotfi, zaynab sadeghi ghadi   +2 more
doaj  

Recent advances in understanding anorexia nervosa. [PDF]

, 2019
Anorexia nervosa is a complex psychiatric illness associated with food restriction and high mortality. Recent brain research in adolescents and adults with anorexia nervosa has used larger sample sizes compared with earlier studies and tasks that test ...
DeGuzman, Marisa C, Frank, Guido KW, Shott, Megan E   +2 more
core  

Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded Protein Response in Human Hepatic Cells

Journal of Pharmacology and Experimental Therapeutics, 2020
Schizophrenia is a mental disease that results in decreased life expectancy and well-being by promoting obesity and sedentary lifestyles. Schizophrenia is treated by antipsychotic drugs. Although the second-generation antipsychotics (SGA), Olanzapine and
Francesca Forno, Yossi Maatuf, Shatha Boukeileh, Priya Dipta, Mohamed Mahameed, Odai Darawshi, Vítor Ferreira, P. Rada, Irma Garcia-Martinez, Einav Gross, A. Priel, Á. Valverde, B. Tirosh   +12 more
semanticscholar   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Connectivity-enhanced diffusion analysis reveals white matter density disruptions in first episode and chronic schizophrenia. [PDF]

, 2018
Reduced fractional anisotropy (FA) is a well-established correlate of schizophrenia, but it remains unclear whether these tensor-based differences are the result of axon damage and/or organizational changes and whether the changes are progressive in the ...
Bearden, Carrie E, Cannon, Tyrone D, Grazioplene, Rachael G, Haut, Kristen, Nuechterlein, Keith H, Subotnik, Kenneth L, Ventura, Joseph   +6 more
core   +3 more sources

Effective Treatment With Olanzapine for Burning Mouth Syndrome With Denture Intolerance in an Older Patient: A Case Report

Gerodontology, EarlyView.
ABSTRACT Introduction Burning mouth syndrome (BMS) is occasionally accompanied by denture intolerance. Case Presentation An 80‐year‐old woman with complaints of residual and relapsed intraoral pain and denture intolerance due to BMS was improved by olanzapine without severe adverse events, and her eating ability was successfully restored.
Motoko Watanabe, Masanao Inokoshi, Chizuko Maeda, Chihiro Takao, Risa Tominaga, Yasuyuki Kimura, Takahiko Nagamine, Akira Toyofuku   +7 more
wiley   +1 more source

Bioequivalence of Aripiprazole Oral Soluble Films and Orally Disintegrating Tablets in Healthy Participants: A Crossover Study

Clinical and Translational Science
Schizophrenia is a serious mental disorder with high disability rates, and antipsychotics, especially second‐generation ones like aripiprazole, are the cornerstone of treatment.
Ruoming Li, Shaojie Yang, Guigang Yang, Xingli Gu, Zuokai Zhang, Taixin Wang, Yunlong Tan, Song Chen   +7 more
doaj   +1 more source

Dorsal Prefrontal Cortex Impairment in Methoxetamine-Induced Psychosis: an 18F-FDG PET/CT Case Study [PDF]

, 2019
Submitted15 June 2018. Accepted 13 December 2018. Epub ahead of print 13 February 2019Novel psychoactive substances (NPSs) have currently become a major public health concern because of relatively easy accessibility to these compounds and difficulty in ...
Covino, Marcello, Di Nicola, Marco, Janiri, Luigi, Martinotti, Giovanni, Mazza, Marianna, Moccia, Lorenzo, Schifano, Fabrizio, Tofani, Anna   +7 more
core   +2 more sources

CYP2D6 Phenotype Influences Aripiprazole Tolerability in Pediatric Patients with Mood Disorders

Journal of child and adolescent psychopharmacology, 2020
Objective: To determine the effect of CYP2D6 metabolizer status on aripiprazole tolerability in pediatric patients with mood disorders. Methods: We retrospectively reviewed electronic medical record data for 277 patients ≤18 years of age (at the time of ...
Sahar A. Jallaq, Mark Verba, J. Strawn, Lisa J. Martin, M. DelBello, L. Ramsey   +5 more
semanticscholar   +1 more source

Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.
Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley   +1 more source