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Minor aristolochic acids from Aristolochia argentina and mass spectral analysis of aristolochic acids

Phytochemistry, 1987
Abstract The minor aristolochic acids isolated from Aristolochia argentina were identified as 6,7-dimethoxy, 6-hydroxy-7-methoxy, 2-hydroxy-8-methoxy and 7-hydroxy-8-methoxy disubstituted derivatives of the 3,4-methylenedioxy-10-nitro-1-phenanthroic acid, respectively. A. argentina also contains the previously reported aristoloside.
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Aristolochic Acid Nephropathy and Balkan Nephropathy

2022
info:eu-repo/semantics ...
Nortier, Joëlle   +2 more
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Eleven aristolochic acid derivatives from Aristolochia cinnabarina

Phytochemistry, 1994
Three new compounds, aristolochic acid IIIa-6-O-beta-D-glucoside, cepharanone-A N-beta-D-glucoside and 2-hydroxy-8-methyloxycepharanone-A, were isolated together with eight known compounds from methanolic extracts of fresh roots of Aristolochia cinnabarina.
H, Li, Y, Sakagami, S, Marumo, X, Chen
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Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer

Current Drug Metabolism, 2013
Aristolochic acid (AA), a plant nephrotoxin and carcinogen, causes aristolochic acid nephropathy (AAN) and its associated urothelial malignancy, and is hypothesized to be responsible for Balkan endemic nephropathy (BEN). The major component of AA, aristolochic acid I (AAI), is the predominant compound responsible for these diseases.
Stiborova, Marie   +4 more
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[Aristolochic acid nephropathy].

Przeglad lekarski, 2009
Aristolochic acid nephropathy is a chronic, fibrosing, interstitial nephritis caused by aristolochic acid (AA), which is a component of the plants of Aristolochiacae family. It was first reported in 1993, in Belgium as a Chinese herb nephropathy, in patients who received a slimming regimen containing AA.
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[Aristolochic acids in herbal medicines].

Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, 1999
Aristolochic acids are nitrophenanthrenes with a carboxylic acid fanction which have been found only among the Aristolochiaceae. In 1993, rapidly progressive interstitial renal fibrosis has been reported in women have been on a slimming regimen including Chinese herbal medicines in Belgium.
S, Sekita   +4 more
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Acute toxicity of aristolochic acid in rodents

Archives of Toxicology, 1987
The acute toxic effects of aristolochic acid (AA) were tested in rats and mice of both sexes. Oral or intravenous administration in high doses was followed by death from acute renal failure within 15 days. Histologically, the predominant features were severe necrosis affecting the renal tubules, atrophy of the lymphatic organs and large areas of ...
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Aristolochic Acid

2018
Rong Yan, Li Li, Guan-Hua Du
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Biosynthesis of aristolochic acid

Chemical Communications (London), 1966
I. D. Spenser, H. P. Tiwari
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