Results 1 to 10 of about 817,904 (149)
Rapid Analysis of Aristolochic Acids and Aristolactams in Houttuyniae Herba by LC–MS/MS [PDF]
Molecules, 2022 Houttuyniae herba, the Saururaceae plant Houttuynia cordata Thunb., has multiple therapeutic effects, including clearing heat, eliminating toxins, reducing swelling, discharging pus, and relieving stagnation.
Yingxue Wu +4 more
exaly +5 more sources
Systematic Overview of Aristolochic Acids: Nephrotoxicity, Carcinogenicity, and Underlying Mechanisms [PDF]
Frontiers in Pharmacology, 2019 Aristolochic acids (AAs) are a group of toxins commonly present in the plants of genus Aristolochia and Asarum, which are spread all over the world.
Aihua Liang
exaly +4 more sources
Protective Effect of Nebivolol against Oxidative Stress Induced by Aristolochic Acids in Endothelial Cells [PDF]
Toxins, 2022 Aristolochic acids (AAs) are powerful nephrotoxins that cause severe tubulointerstitial fibrosis. The biopsy-proven peritubular capillary rarefaction may worsen the progression of renal lesions via tissue hypoxia.
Vanessa Tagliatti +2 more
exaly +4 more sources
Temporal Variation of Aristolochia chilensis Aristolochic Acids during Spring [PDF]
Molecules, 2015 In this communication, we report the springtime variation of the composition of aristolochic acids (AAs) in Aristolochia chilensis leaves and stems. The dominant AA in the leaves of all samples, which were collected between October and December, was AA-I
Alejandro Urzúa, Angel Olguin
exaly +4 more sources
Aristolochic Acids: Newly Identified Exposure Pathways of this Class of Environmental and Food-Borne Contaminants and its Potential Link to Chronic Kidney Diseases [PDF]
Toxics, 2019 Aristolochic acids (AAs) are nitrophenanthrene carboxylic acids naturally produced by Aristolochia plants. These plants were widely used to prepare herbal remedies until AAs were observed to be highly nephrotoxic and carcinogenic to humans.
Chi-Kong Chan, Chan Simon Wan
exaly +4 more sources
Biomolecules, 2021 Aristolochic acids are known for nephrotoxicity, and implicated in multiple cancer types such as hepatocellular carcinomas demonstrated by recent studies.
Tingjun Xu +5 more
doaj +2 more sources
Foods, 2022 In this study, a new and simple method was established for the simultaneous determination of analogues of aristolochic acids (aristolochic acid I, aristolochic acid II, aristolactam I and aristolactam AII) in Houttuynia cordata by ultra-high performance ...
Xuan Yu +7 more
doaj +1 more source
Overview of aristolochic acid nephropathy: an update [PDF]
Kidney Research and Clinical Practice, 2023 Aristolochic acid nephropathy (AAN) is a rapidly progressive renal interstitial fibrosis caused by medical or environmental exposure to aristolochic acid (AA).
Qingqing Zhou +4 more
doaj +1 more source
Balkan Journal of Medical Genetics, 2022 The term “aristolochic acid nephropathy” (AAN) is used to include any form of toxic interstitial nephropathy that is caused either by ingestion of plants containing aristolochic acids (AA) or by the environmental contaminants in food such as in Balkan ...
Bašić D +3 more
doaj +1 more source
Molecules, 2023 Aristolochic acids (AAs) are a toxic substance present in certain natural plants. Direct human exposure to these plants containing AAs leads to a severe and irreversible condition known as aristolochic acid nephropathy (AAN).
Changhong Wang +5 more
doaj +1 more source