Results 41 to 50 of about 817,904 (149)

Genome-wide transcriptional analysis of Aristolochia manshuriensis induced gastric carcinoma

Pharmaceutical Biology, 2020
Context Aristolochia manshuriensis Kom (Aristolochiaceae) (AMK) is known for toxicity and mutagenicity. Objective The tumorigenic role of AMK has yet to be understood. Materials and methods AMK extracts were extracted from root crude drug.
Lianmei Wang, Chunying Li, Jingzhuo Tian, Jing Liu, Yong Zhao, Yan Yi, Yushi Zhang, Jiayin Han, Chen Pan, Suyan Liu, Nuo Deng, Zhong Xian, Guiqin Li, Xin Zhang, Aihua Liang   +14 more
doaj   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Quality vs Quantity: The Effect of Aristolochic Acids on Preference and Performance of a Non-Specialist Herbivore [PDF]

, 2011
As immobile organisms, plants have evolved many strategies for defense against herbivores. These defenses can be physical, such as thorns, or chemical, such as antifeedant compounds.
Jeude, Samantha Eileen
core   +1 more source

Advanced Sorbent Materials in Solid‐Phase Extraction: A Decade of Innovation and Future Perspectives

Chemistry–Methods, Volume 6, Issue 8, August 2026.
This review systematically summarizes five families of advanced sorbent materials for solid‐phase extraction (SPE): nanocarbons, porous frameworks (MOFs/COFs), smart polymers, biomass‐derived sorbents, and multifunctional composites. Key molecular interactions (π–π stacking, hydrogen bonding, electrostatic attraction, host–guest recognition) are ...
Xingchen Wang, Linling Guo, Jingyi Yue, Wenxiao Zhuo, Shunli Ji   +4 more
wiley   +1 more source

Aristolochic acids in Aristolochia chilensis and the Aristolochia-FEEDER Battus Archidamas (Lepidoptera)

, 1983
The larval stages of Battus archidamas, the only Papilionoid butterfly living in Chile, feed on the aerial parts of Aristolochia chilensis. The food material contains aristolochic acids, and so do the insects, which retain these compounds after ...
Guillermo Salgado, Bruce K. Cassels, Alejandro Urzúa, Gert Eckhardt   +3 more
core   +1 more source

Prognostic role of stromal tumor-infiltrating lymphocytes in locally advanced upper tract urothelial carcinoma: A retrospective multicenter study (TSU-02 study)

OncoImmunology, 2021
Locally advanced upper urinary tract urothelial carcinoma (UTUC) exhibits high recurrence and metastasis rates even after radical nephroureterectomy. Adjuvant immunotherapy can be a reasonable option, and a simple, low-cost, and effective biomarker is ...
Sida Cheng, Wenlong Zhong, Kun Xia, Peng Hong, Rongcheng Lin, Bo Wang, Xinfei Li, Junyu Chen, Zining Liu, Hongxian Zhang, Cheng Liu, Liefu Ye, Lulin Ma, Tianxin Lin, Xuesong Li, Jian Huang, Liqun Zhou   +16 more
doaj   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source