Results 1 to 10 of about 366,391 (138)

Early detection of Balkan endemic nephropathy in Bosanska Posavina. [PDF]

Bosn J Basic Med Sci, 2010
Balkan endemic nephropathy (BEN) is a chronic tubulointersticial nephropathy that is diagnosed in a few agrarian regions of Balkan. Even tough numerous dilemmas and conflicting opinions regarding BEN etiology are encountered in literature, prevailing ...
Mesić E.
europepmc   +4 more sources

Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy. [PDF]

Medicina (Kaunas), 2019
Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons.
Djukanović L, Ležaić V, Bukvić D, Mirković D, Marić I.   +4 more
europepmc   +4 more sources

Association of SOD2 (rs4880) and GPX1 (rs1050450) Gene Polymorphisms with Risk of Balkan Endemic Nephropathy and its Related Tumors. [PDF]

Medicina (Kaunas), 2019
Background and Objectives: Experimental data show that superoxide dismutase 2 (SOD2) is involved in ochratoxin (OTA)-induced nephrotoxicity, whereas clinical data indicate the role of SOD2 rs4880 or glutathione peroxidase 1 (GPX1) rs1050450 polymorphisms
Dragicevic B, Suvakov S, Jerotic D, Reljic Z, Djukanovic L, Zelen I, Pljesa-Ercegovac M, Savic-Radojevic A, Simic T, Dragicevic D, Matic M.   +10 more
europepmc   +4 more sources

Is increased susceptibility to Balkan endemic nephropathy in carriers of common GSTA1 (*A/*B) polymorphism linked with the catalytic role of GSTA1 in ochratoxin a biotransformation? Serbian case control study and in silico analysis. [PDF]

Toxins (Basel), 2014
Although recent data suggest aristolochic acid as a putative cause of Balkan endemic nephropathy (BEN), evidence also exists in favor of ochratoxin A (OTA) exposure as risk factor for the disease.
Reljic Z, Zlatovic M, Savic-Radojevic A, Pekmezovic T, Djukanovic L, Matic M, Pljesa-Ercegovac M, Mimic-Oka J, Opsenica D, Simic T.   +9 more
europepmc   +4 more sources

Molecular Characterization of Microrna Interference and Aristolochic Acid Intoxication Found in Upper Tract Urothelial Carcinoma in Patients with Balkan Endemic Nephropathy: A Systematic Review of the Current Literature. [PDF]

Balkan J Med Genet, 2023
The term “aristolochic acid nephropathy” (AAN) is used to include any form of toxic interstitial nephropathy that is caused either by ingestion of plants containing aristolochic acids (AA) or by the environmental contaminants in food such as in Balkan ...
Bašić D, Ignjatović I, Janković Veličković L, Veljković A.   +3 more
europepmc   +2 more sources

GPX3 rs8177412 Polymorphism Modifies Risk of Upper Urothelial Tumors in Patients with Balkan Endemic Nephropathy. [PDF]

Medicina (Kaunas), 2023
Current data suggest that aristolochic acid (AA) exposure is a putative cause of Balkan endemic nephropathy (BEN), a chronic kidney disease strongly associated with upper tract urothelial carcinoma.
Radic Savic Z, Coric V, Vidovic S, Vidovic V, Becarevic J, Milovac I, Reljic Z, Mirjanic-Azaric B, Skrbic R, Gajanin R, Matic M, Simic T.   +11 more
europepmc   +2 more sources

Arterial Stiffness in Balkan Endemic Nephropathy, an Environmental Form of Aristolochic Acid Nephropathy. [PDF]

Front Cardiovasc Med, 2018
Balkan endemic nephropathy (BEN), an environmental form of aristolochic acid nephropathy is characterized with later onset and milder forms of hypertension (HT). Thus, we hypothesized that arterial stiffness progresses slower in BEN patients resulting in
Premužić V, Ivković V, Leko N, Stipančić Ž, Karanović S, Jelaković A, Vuković Brinar I, Dika Ž, Jelaković B.   +8 more
europepmc   +2 more sources

Urine Metabolomic Signature of People Diagnosed with Balkan Endemic Nephropathy and Other Types of Chronic Kidney Disease Compared with Healthy Subjects in Romania. [PDF]

Metabolites, 2023
Metabolomic analysis methods were employed to determine biomarkers for various chronic kidney diseases (CKDs). Modern analytical methods were developed and applied successfully to find a specific metabolomic profile in urine samples from CKD and Balkan ...
Ordodi VL, Hădărugă NG, Hădărugă DI, Lukinich-Gruia AT, Mărgineanu M, Tatu CA, Păunescu V.   +6 more
europepmc   +2 more sources

Expression of Basal Compartment and Superficial Markers in Upper Tract Urothelial Carcinoma Associated with Balkan Endemic Nephropathy, a Worldwide Disease. [PDF]

Biomedicines
The aim of this study was to determine the association of basal compartment and superficial markers, comprising CK5/6, CD44, CK20, and the pathological characteristics of upper tract urothelial carcinoma (UTUC) associated with Balkan endemic nephropathy (
Jankovic Velickovic L, Ristic Petrovic A, Dolicanin Z, Stojnev S, Velickovic F, Basic D.   +5 more
europepmc   +2 more sources

Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN). [PDF]

BMC Med Genet, 2012
Background Balkan Endemic Nephropathy (BEN) is late-onset kidney disease thought to arise from chronic exposure to aristolochic acid, a phytotoxin that contaminates wheat supplies in rural areas of Eastern Europe.
Wooding SP, Atanasova S, Gunn HC, Staneva R, Dimova I, Toncheva D.   +5 more
europepmc   +2 more sources