Pro- and antiapoptotic markers in upper tract urothelial carcinoma associated with Balkan endemic nephropathy. [PDF]
The role of aristolochic acid in the etiology of Balkan endemic nephropathy (BEN) and associated upper-tract urothelial carcinoma (UTUC) has been recently confirmed.
Jankovic-Velickovic L +7 more
europepmc +2 more sources
Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. [PDF]
TASK-2, a member of the Two-Pore Domain (K2P) subfamily of K+ channels, is encoded by the KCNK5 gene. The channel is expressed primarily in renal epithelial tissues and a potentially deleterious missense variant in KCNK5 has recently been shown to be ...
Reed AP +3 more
europepmc +2 more sources
Values of Alpha 1 Microglobulin Does Not Differ between Individuals with and without Family History of Balkan Endemic Nephropathy. [PDF]
Aim. The aim of this study was to compare urinary alpha 1 microglobulin (A1MG) in healthy individuals with and without family burden for Balkan endemic nephropathy (BEN) in an endemic village. Methods. Otherwise healthy inhabitants with microalbuminuria
Aleckovic-Halilovic M +7 more
europepmc +2 more sources
Trend of Balkan endemic nephropathy patients on renal replacement therapy in Bosnia from 2003 through 2005. [PDF]
The aim of this study is to evaluate epidemiological status of Balkan endemic nephropathy (BEN) patients on renal replacement therapy (RRT) in Bosnia from 2003 through 2005.
Imamović G, Zerem E, Omerović S.
europepmc +2 more sources
Comparative (1)H NMR metabolomic urinalysis of people diagnosed with Balkan endemic nephropathy, and healthy subjects, in Romania and Bulgaria: a pilot study. [PDF]
1H NMR spectroscopy of urine has been applied to exploring metabolomic differences between people diagnosed with Balkan endemic nephropathy (BEN), and treated by haemodialysis, and those without overt renal disease in Romania and Bulgaria.
Mantle P +5 more
europepmc +2 more sources
Predictive Markers for Malignant Urothelial Transformation in Balkan Endemic Nephropathy: A Case-Control Study. [PDF]
Kocic G +8 more
europepmc +2 more sources
Balkan endemic nephropathy-current status and future perspectives. [PDF]
Pavlović NM.
europepmc +2 more sources
Whole genome methylation array analysis reveals new aspects in Balkan endemic nephropathy etiology. [PDF]
Background Balkan endemic nephropathy (BEN) represents a chronic progressive interstitial nephritis in striking correlation with uroepithelial tumours of the upper urinary tract.
Staneva R +16 more
europepmc +4 more sources
NGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathy. [PDF]
Balkan endemic nephropathy (BEN) is a familial chronic tubulointerstitial disease with insidious onset and slow progression leading to terminal renal failure. The results of molecular biological investigations propose that BEN is a multifactorial disease
Toncheva D +20 more
europepmc +3 more sources
Aristolochic acids (AAs) are a toxic substance present in certain natural plants. Direct human exposure to these plants containing AAs leads to a severe and irreversible condition known as aristolochic acid nephropathy (AAN).
Changhong Wang +5 more
doaj +1 more source

