Is Increased Susceptibility to Balkan Endemic Nephropathy in Carriers of Common GSTA1 (*A/*B) Polymorphism Linked with the Catalytic Role of GSTA1 in Ochratoxin A Biotransformation? Serbian Case Control Study and In Silico Analysis [PDF]
Toxins, 2014 Although recent data suggest aristolochic acid as a putative cause of Balkan endemic nephropathy (BEN), evidence also exists in favor of ochratoxin A (OTA) exposure as risk factor for the disease.
Zorica Reljic +9 more
doaj +2 more sources
Assessment of Retinal Microangiopathy in Patients with Balkan Endemic Nephropathy Using Optical Coherence Tomography Angiography—A Pilot Study [PDF]
MedicinaBackground and Objectives: It is well known that alterations in microvascular structure and function contribute to the development of ocular, renal, and cardiovascular diseases.
Jasmina Djordjevic-Jocic +7 more
doaj +2 more sources
Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. [PDF]
PLoS ONE, 2016 TASK-2, a member of the Two-Pore Domain (K2P) subfamily of K+ channels, is encoded by the KCNK5 gene. The channel is expressed primarily in renal epithelial tissues and a potentially deleterious missense variant in KCNK5 has recently been shown to be ...
Alan P Reed +3 more
doaj +2 more sources
Correction: Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. [PDF]
PLoS ONE, 2016 [This corrects the article DOI: 10.1371/journal.pone.0156456.].
Alan P Reed +3 more
doaj +2 more sources
Values of Alpha 1 Microglobulin Does Not Differ between Individuals with and without Family History of Balkan Endemic Nephropathy [PDF]
International Journal of Nephrology, 2014 Aim. The aim of this study was to compare urinary alpha 1 microglobulin (A1MG) in healthy individuals with and without family burden for Balkan endemic nephropathy (BEN) in an endemic village. Methods. Otherwise healthy inhabitants with microalbuminuria
Mirna Aleckovic-Halilovic +7 more
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EVIDENCE OF A VIRAL ÆTIOLOGY IN ENDEMIC (BALKAN) NEPHROPATHY [PDF]
Lancet, The, 1975 Segemental and focal pathological changes were found in the glomeruli and tubules of postoperative renal-biopsy specimens from seven cases of clinically confirmed endemic (Balkan) nephropathy. In the glomeruli, there was mesangial reaction and segmental thickening of the basement membrane with subendothelial and membranous depositions.
Apostolov, K, Spasic, P, Bojanic, N
exaly +3 more sources
Increased blood pressure in adult offspring of families with Balkan Endemic Nephropathy: a prospective study [PDF]
BMC Nephrology, 2006 Background Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manifest increased blood pressure.
Georgieva Rossitza B +5 more
doaj +2 more sources
Trend of Balkan Endemic Nephropathy Patients on Renal Replacement Therapy in Bosnia From 2003 Through 2005 [PDF]
Biomolecules & Biomedicine, 2007 The aim of this study is to evaluate epidemiological status of Balkan endemic nephropathy (BEN) patients on renal replacement therapy (RRT) in Bosnia from 2003 through 2005.
Goran Imamović +2 more
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Aristolochic acid and the etiology of endemic (Balkan) nephropathy [PDF]
Proceedings of the National Academy of Sciences, 2007 Endemic (Balkan) nephropathy (EN), a devastating renal disease affecting men and women living in rural areas of Bosnia, Bulgaria, Croatia, Romania, and Serbia, is characterized by its insidious onset, invariable progression to chronic renal failure and a strong association with transitional cell (urothelial) carcinoma of the upper ...
Grollman, Arthur P. +17 more
openaire +8 more sources
Comparative 1H NMR Metabolomic Urinalysis of People Diagnosed with Balkan Endemic Nephropathy, and Healthy Subjects, in Romania and Bulgaria: A Pilot Study [PDF]
Toxins, 2011 1H NMR spectroscopy of urine has been applied to exploring metabolomic differences between people diagnosed with Balkan endemic nephropathy (BEN), and treated by haemodialysis, and those without overt renal disease in Romania and Bulgaria.
Draga Toncheva +5 more
doaj +2 more sources