Results 1 to 10 of about 309 (88)

Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system

Redox Biology, 2022
Lycopene (LYC) is a carotenoid, has antioxidant properties. This study investigated whether lycopene attenuates aristolochic acids (AAs) -induced chronic kidney disease.
Yu Wang, Zhihui Liu, Jun Ma, Qingyang Xv, Hongxin Gao, Hang Yin, Ge Yan, Xiaowen Jiang, Wenhui Yu   +8 more
doaj   +3 more sources

Study of the Contents of Analogues of Aristolochic Acid in Houttuynia cordata by Ultra-High Performance Liquid Chromatography Tandem Mass Spectrometry

Foods, 2022
In this study, a new and simple method was established for the simultaneous determination of analogues of aristolochic acids (aristolochic acid I, aristolochic acid II, aristolactam I and aristolactam AII) in Houttuynia cordata by ultra-high performance ...
Xuan Yu, Yuan Gao, Ying Xu, Xian Guo, Lan Guo, Ting Tan, Fan Liu, Yiqun Wan   +7 more
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Computational Analysis of Naturally Occurring Aristolochic Acid Analogues and Their Biological Sources

Biomolecules, 2021
Aristolochic acids are known for nephrotoxicity, and implicated in multiple cancer types such as hepatocellular carcinomas demonstrated by recent studies.
Tingjun Xu, Weiming Chen, Junhong Zhou, Jingfang Dai, Yingyong Li, Yingli Zhao   +5 more
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Preventive effect of icariin on transition from acute kidney injury to chronic kidney disease in mouse model

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To investigate the effect of icariin on the transition from acute kidney disease (AKI) to chronic kidney disease (CKD) in mice and the possible mechanism.Methods·C57BL/6 mice were intraperitoneally injected with aristolochic acid for 2 weeks to
XIE Lin, CHENG Ye, ZHENG Qimin, ZHANG Xi, FU Lili, CHEN Min, WANG Yi, MEI Changlin, XIE Jingyuan, GU Xiangchen   +9 more
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ARISTOLOCHIC ACID I DETERMINATION IN ARISTOLOCHIA CLEMATITIS L. RAW MATERIALS BY HPLC METHOD [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2020
Aristolochia clematitis has long ago been applied in Asian traditional medicine and demonstrates multidirectional pharmacological activity. Contemporary research has confirmed its expressed antimicrobial activity.
Artur Martynov, Larisa Andryukova, Viktoriia Kyslychenko, Nadiia Burda, Lala Pohodina   +4 more
doaj   +1 more source

Rapid Analysis of Aristolochic Acid Analogues in Traditional Chinese Patent Medicine by LC-MS/MS

Journal of Analytical Methods in Chemistry, 2020
Aristolochic acids have been demonstrated to have renal toxicity, cause carcinogenesis, and may cause gene mutations. A series of risk control measurements have been adopted worldwide since 1990s.
Jing Liu, Yang Liu, Yingxue Wu, Zhong Dai, Shuangcheng Ma   +4 more
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Molecular Characterization of Microrna Interference and Aristolochic Acid Intoxication Found in Upper Tract Urothelial Carcinoma in Patients with Balkan Endemic Nephropathy: A Systematic Review of the Current Literature

Balkan Journal of Medical Genetics, 2022
The term “aristolochic acid nephropathy” (AAN) is used to include any form of toxic interstitial nephropathy that is caused either by ingestion of plants containing aristolochic acids (AA) or by the environmental contaminants in food such as in Balkan ...
Bašić D, Ignjatović I, Janković Veličković Lj, Veljković A   +3 more
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De novo upper tract urothelial carcinoma after renal transplantation: a single-center experience in China

BMC Urology, 2023
Highlights Both higher tumor staging and positive lymph node status were associated with a worse cancer-specific survival in patients with post-transplant de novo UTUC. Aristolochic acid was associated with multifocality of tumors and higher incidence of
Shixin Li, Jian Zhang, Ye Tian, Yichen Zhu, Yuwen Guo, Zhipeng Wang, Yang Yang, Guangpu Ding, Jun Lin   +8 more
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Isolation of Aristolochic Acids from Aristolochia Bracteolata and Studies of their Antioxidant Activities

Sultan Qaboos University Journal for Science, 2004
The isolation and structural elucidation of aristolochic acid-A and aristolochic acid-D from Omani Aristolochia bracteolata plant is reported. Antioxidant activities of these two natural products were evaluated for their capacity to reduce Mo(VI) to Mo(V)
Saleh Al-Busafi, Munir Al-Harthi, Bushra Al-Sabahi   +2 more
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Two New Aristolochic Acid Analogues from the Roots of Aristolochia contorta with Significant Cytotoxic Activity

Molecules, 2020
Twelve compounds, including two new aristolochic acid analogues with a formyloxy moiety (9–10) and 10 known aristolochic acid derivates (1–8 and 11–12), were obtained from the roots of Aristolochiacontorta.
Hong-Jian Ji, Jia-Yuan Li, Shi-Fei Wu, Wen-Yong Wu, Chang-Liang Yao, Shuai Yao, Jian-Qing Zhang, De-An Guo   +7 more
doaj   +1 more source