Overview of aristolochic acid nephropathy: an update [PDF]
Kidney Research and Clinical Practice, 2023 Aristolochic acid nephropathy (AAN) is a rapidly progressive renal interstitial fibrosis caused by medical or environmental exposure to aristolochic acid (AA).
Qingqing Zhou +4 more
doaj +4 more sources
Beyond Ingestion: Nasal Inhalation-Induced Aristolochic Acid Nephropathy from a Traditional Herbal Remedy – A Case Report [PDF]
Glomerular DiseasesIntroduction: Aristolochic acid nephropathy (AAN), a progressive form of interstitial nephritis, is predominantly associated with the oral ingestion of herbal remedies containing aristolochic acid (AA). Case Presentation: This report details a
Talerngsak Kanjanabuch +4 more
doaj +3 more sources
Parametric MRI Detects Aristolochic Acid Induced Acute Kidney Injury [PDF]
Tomography, 2022 Exposure to aristolochic acid (AA) is of increased concern due to carcinogenic and nephrotoxic effects, and incidence of aristolochic acid nephropathy (AAN) is increasing.
Yingjie Mei +11 more
doaj +3 more sources
Aristolochic Acid Induced Suicidal Erythrocyte Death
Kidney & Blood Pressure Research, 2014 Background/Aims: Aristolochic Acid, a component of Aristolochia plants, has been shown to cause acute kidney injury, renal aristolochic acid nephropathy, Balkan endemic nephropathy, and urothelial carcinoma.
Abaid Malik +5 more
doaj +2 more sources
Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways [PDF]
Advanced Science, Volume 13, Issue 19, 2 April 2026.The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan +20 more
wiley +2 more sources
Detection and Removal of Aristolochic Acid in Natural Plants, Pharmaceuticals, and Environmental and Biological Samples: A Review [PDF]
Molecules, 2023 Aristolochic acids (AAs) are a toxic substance present in certain natural plants. Direct human exposure to these plants containing AAs leads to a severe and irreversible condition known as aristolochic acid nephropathy (AAN).
Changhong Wang +5 more
doaj +2 more sources
Environmental Health Insights, 2011 Background Aristolochic Acids (AAs) are major components of plants in Aristolochia and have been found to be nephrotoxic, carcinogenic and mutagenic. Herein reported are the isolation, identification and quantity determination methods of Aristolochic ...
Abdelgadir A. Abdelgadir +2 more
doaj +2 more sources
Worldwide research trends on aristolochic acids (1957-2017): Suggestions for researchers.
PLoS ONE, 2019 Aristolochic acids and their derivatives are components of many traditional medicines that have been used for thousands of years, particularly in Asian countries.
Qiang Zhou +7 more
doaj +2 more sources
Aristolochic acid I exposure decreases oocyte quality [PDF]
Frontiers in Cell and Developmental Biology, 2022 Oocyte quality is a determinant of a successful pregnancy. The final step of oocyte development is oocyte maturation, which is susceptible to environmental exposures.
Weidong Li +11 more
doaj +2 more sources
Is Aristolochic Acid Really the Cause of the Balkan Endemic Nephropathy? [PDF]
Journal of Controversies in Biomedical Research, 2016 In recent years, aristolochic acid has been promoted vigorously as the causal agent of the Balkan endemic nephropathy because of similarities to some other nephropathies, association with DNA adducts and a perception of human exposure via bread. Critical
Peter George Mantle +2 more
doaj +2 more sources