Results 41 to 50 of about 2,520,275 (163)

Patterns of renal pathology in Chinese patients with systemic sclerosis undergoing renal biopsy at a tertiary medical center

Journal of International Medical Research, 2020
Objective We investigated renal injury characteristics in Chinese patients with systemic sclerosis (SSc) who had undergone renal biopsy. Methods We searched the medical records of patients with SSc who were hospitalized at Peking Union Medical College ...
Xiao-yu Cao, He Liu, Dong Xu, Meng-tao Li, Qian Wang, Li Jiang, Yong Hou, Li-xiu Zhu, Xiao-feng Zeng   +8 more
doaj   +1 more source

Hong Kong Poison Information Centre: Annual report 2022

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Background The Hong Kong Poison Information Centre (HKPIC) has been providing consultation services to healthcare professionals and collecting epidemiological data on poisoning in Hong Kong since 2005. Objective To analyse and report the poisoning data from HKPIC in 2022.
Tin Yat Anthony Chow, Chi Keung Chan, Shan Liu, Sze Hong Ng, Man Li Tse   +4 more
wiley   +1 more source

Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN)

BMC Medical Genetics, 2012
Background Balkan Endemic Nephropathy (BEN) is late-onset kidney disease thought to arise from chronic exposure to aristolochic acid, a phytotoxin that contaminates wheat supplies in rural areas of Eastern Europe.
Wooding Stephen P, Atanasova Srebrena, Gunn Howard C, Staneva Rada, Dimova Invanka, Toncheva Draga   +5 more
doaj   +1 more source

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

The Disturbance of Hepatic and Serous Lipids in Aristolochic Acid Ι Induced Rats for Hepatotoxicity Using Lipidomics Approach

Molecules, 2019
Aristolochic acid I (AAI) was regarded as the major toxic component of aristolochic acid (AA). In addition to aristolochic acid nephropathy (AAN), liver cancers induced by AAI has aroused increasing attention recently.
Junyi Zhou, Yifei Yang, Hongjie Wang, Baolin Bian, Jian Yang, Xiaolu Wei, Yanyan Zhou, Nan Si, Haiyu Zhao   +8 more
doaj   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Integration of Transcriptomic and Metabolomic Data to Compare the Hepatotoxicity of Neonatal and Adult Mice Exposed to Aristolochic Acid I

Frontiers in Genetics, 2022
Aristolochic acid (AA) is a group of structurally related compounds what have been used to treat various diseases in recent decades. Aristolochic acid I (AAI), an important ingredient, has been associated with tumorigenesis.
Zhi-e Fang, Zhi-e Fang, Zhi-e Fang, Chunyu Wang, Chunyu Wang, Ming Niu, Ming Niu, Tingting Liu, Tingting Liu, Lutong Ren, Lutong Ren, Qiang Li, Qiang Li, Zhiyong Li, Zhiyong Li, Ziying Wei, Ziying Wei, Li Lin, Li Lin, Wenqing Mu, Wenqing Mu, Yuan Gao, Xiaohe Xiao, Xiaohe Xiao, Xiaohe Xiao, Zhaofang Bai, Zhaofang Bai   +26 more
doaj   +1 more source

Advanced Sorbent Materials in Solid‐Phase Extraction: A Decade of Innovation and Future Perspectives

Chemistry–Methods, Volume 6, Issue 8, August 2026.
This review systematically summarizes five families of advanced sorbent materials for solid‐phase extraction (SPE): nanocarbons, porous frameworks (MOFs/COFs), smart polymers, biomass‐derived sorbents, and multifunctional composites. Key molecular interactions (π–π stacking, hydrogen bonding, electrostatic attraction, host–guest recognition) are ...
Xingchen Wang, Linling Guo, Jingyi Yue, Wenxiao Zhuo, Shunli Ji   +4 more
wiley   +1 more source

Unambiguous detection of multiple TP53 gene mutations in AAN-associated urothelial cancer in Belgium using laser capture microdissection.

PLoS ONE, 2014
In the Balkan and Taiwan, the relationship between exposure to aristolochic acid and risk of urothelial neoplasms was inferred from the A>T genetic hallmark in TP53 gene from malignant cells.
Selda Aydin, Anne-France Dekairelle, Jérôme Ambroise, Jean-François Durant, Michel Heusterspreute, Yves Guiot, Jean-Pierre Cosyns, Jean-Luc Gala   +7 more
doaj   +1 more source

Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX-III, a D49 phospholipase A₂ from Bothrops pirajai venom

BMC Complementary and Alternative Medicine, 2012
Background Harpalycin 2 (HP-2) is an isoflavone isolated from the leaves of Harpalyce brasiliana Benth., a snakeroot found in northeast region of Brazil and used in folk medicine to treat snakebite. Its leaves are said to be anti-inflammatory.
Ximenes Rafael M, Alves Renata S, Pereira Ticiana P, Araújo Renata M, Silveira Edilberto R, Rabello Marcelo M, Hernandes Marcelo Z, Soares Veronica C G, Bristot Daniel, Pires Camila L, Toyama Daniela O, Gaeta Henrique H, Monteiro Helena S A, Toyama Marcos H   +13 more
doaj   +1 more source