Results 61 to 70 of about 2,520,275 (163)
Genetic Variation in Chemical Defence Affects Protection of an Herbivorous Insect Against Predation
Molecular Ecology, Volume 35, Issue 9, May 2026.ABSTRACT Genetic variation contributes to intraspecific differences in the chemical defence in many insect species, yet the underlying genetic mechanisms remain poorly understood. The horseradish flea beetle, Phyllotreta armoraciae, sequesters glucosinolates from its horseradish host plant and activates them using endogenous myrosinase enzymes.
Johannes Körnig +9 more
wiley +1 more source
Study on metabolism of plant carcinogen aristolochic acid I
, 2022 Aristolochic acids (AA) are natural compounds present in plant species of Aristolochiaceae. These plant alkaloids exhibit nephrotoxic effects and are human carcinogens.
Dedíková, Alena
core
International Journal of Electrochemical Science, 2016 Aristolochic acids (1 and 2), a component in medicinal plants, have been reported as the cause of end-stage renal failure. For the identification and quantity determination of aristolochic acid a and 2 (AA-1 and AA-2) in Radix Aucklandiae, a liquid ...
Junping Zhang +8 more
doaj +1 more source
, 2016 Investigation of the chemical constituents of Aristolochia maurorum growing wild in Jordan resulted in the isolation and characterisation of one new compound in addition to 19 known compounds.
Mohammed B. Al-Barham (3118923) +3 more
core +1 more source
Advanced Science, Volume 13, Issue 19, 2 April 2026.Mechanisms of Aristolochic Acid Resistance Why can butterflies feast on toxic Aristolochia plants, while humans are severely harmed by the same toxins? This study unravels the molecular secrets behind the Red‐bodied Swallowtail's resistance to aristolochic acids, offering evolutionary clues to mitigate AA‐associated diseases in humans. More details can
Yang Luan +20 more
wiley +1 more source
Short-term toxicity of aristolochic acid, aristolochic acid-I and aristolochic acid-II in rats.
, 2012 [[abstract]]We compared the short-term toxicity of toxic components of aristolochic acid in rats. Twenty-four female Wistar rats were divided into 4 groups and treated orally every 3-days with 10 mg/kg each of aristolochic acid, aristolochic acid-I and ...
謝宥諒;Hsieh, You-Liang
core
Molecular mechanism of carcinogenicity of aristolochic acid [PDF]
, 2013 Aristolochic acids (AA) are carcinogenic and nephrotoxic alkaloids from Aristolochia species. Aristolochic acid I (AAI), the major component of AA, causes the development of Aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN).
Levová, Kateřina
core
Leveraging extracellular vesicle biology for novel tests and therapeutics for kidney fibrosis
Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.Extracellular vesicles (EVs) are bilipid membrane‐encased nanoparticles that play critical roles as cell‐to‐cell messengers and waste management mechanisms. EVs cargos can be leveraged as biomarkers to develop minimally invasive tests for kidney fibrosis and guide personalised mechanism‐driven care.
Chin‐Ya Sophie Chiang +3 more
wiley +1 more source
, 2015 This in vitro study aimed to determine the effects of a Panax ginseng extract on aristolochic acid-mediated toxicity in HK-2 cells. A methanolic extract of ginseng (50 μg/mL) was able to reduce cell survival after treatment with 50 μM aristolochic acid ...
Nortier, Joëlle +5 more
core +1 more source
Advanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney +3 more
wiley +1 more source