Results 71 to 80 of about 2,520,275 (163)

ELEVEN ARISTOLOCHIC ACID-DERIVATIVES FROM ARISTOLOCHIA-CINNABARINA

, 1994
Three new compounds, aristolochic acid IIIa-6-O-beta-D-glucoside, cepharanone-A N-beta-D-glucoside and 2-hydroxy-8-methyloxycepharanone-A, were isolated together with eight known compounds from methanolic extracts of fresh roots of Aristolochia ...
SAKAGAMI, Y, LI, H, MARUMO, S, CHEN, XM
core  

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation. [PDF]

, 2008
Aristolochic acid contamination in herbal remedies leads to interstitial fibrosis, tubular atrophy, and renal failure in humans. To study the cellular mechanisms contributing to the pathophysiology of this renal disease, we studied Wistar rats treated ...
Nortier, Joëlle, Salmon, I.J., Decaestecker, C., Pozdzik, Agnieszka, Van den Branden, C., Van den Branden, C, Verbeelen, Dirk, Vanherweghem, Jean-Louis, Vanherweghem, J.-L., Pozdzik, A.A., Debelle, F.D., Salmon, Isabelle, Debelle, Frédéric, Verbeelen, D., Nortier, J.L., Deschodt Lanckman, Monique, Deschodt-Lanckman, M.M., Decaestecker, Christine   +17 more
core   +1 more source

Quantitation of aristolochic acid using high performance liquid chromatography with photodiode array detection

, 2001
Central Institute of Medicinal and Aromatic Plants, Lucknow-226 015, India E-mail: cimap@satyam.net.in Fax : 91-0522-342666 Manuscript received 11 August 2000. revised 26 March 2001, accepted 31 March 2001 A rapid, sensitive and reproducible HPLC
R. K. Verma, M. M. Gupta, B. L. Singh, D. V. Singh, S. Banerji, Sushil Kumar   +5 more
core   +1 more source

Aristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients

, 2018
Gengyan Xiong,1,* Lin Yao,1,* Peng Hong,1,* Li Yang,2 Weimin Ci,3 Libo Liu,1 Qun He,1 Kan Gong,1 Xuesong Li,1 Liqun Zhou1 1Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center,
Yao L, Li X, Zhou L, Yang L, Liu L, Gong K, Hong P, He Q, Ci W, Xiong G   +9 more
core  

Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer

, 2013
Aristolochic acid (AA), a plant nephrotoxin and carcinogen, causes aristolochic acid nephropathy (AAN) and its associated urothelial malignancy, and is hypothesized to be responsible for Balkan endemic nephropathy (BEN).
Schmeiser, Heinz H, Frei, Eva, Stiborova, Marie, Martínek, Vaclav, Arlt, Volker M; id_orcid   +4 more
core   +1 more source

Increased risk of urinary tract cancer in ESRD patients associated with usage of Chinese herbal products suspected of containing aristolochic acid.

PLoS ONE, 2014
IntroductionBoth end-stage renal disease (ESRD) and urothelial cancer (UC) are associated with the consumption of Chinese herbal products containing aristolochic acid (AA) by the general population.
Shuo-Meng Wang, Ming-Nan Lai, Alan Wei, Ya-Yin Chen, Yeong-Shiau Pu, Pau-Chung Chen, Jung-Der Wang   +6 more
doaj   +1 more source

Medicinally Used Asarum Species: High-Resolution LC-MS Analysis of Aristolochic Acid Analogs and In vitro Toxicity Screening in HK-2 Cells

Frontiers in Pharmacology, 2017
Species of Asarum are used in traditional Chinese medicine and, similar to members of the genus Aristolochia, they contain aristolochic acid analogs (AAAs). These compounds are known for their nephrotoxic and carcinogenic effects.
Johanna Michl, Olusheyi Bello, Geoffrey C. Kite, Monique S. J. Simmonds, Michael Heinrich   +4 more
doaj   +1 more source

Survey of the Occurrence of Aristolochic Acid in Fangchi obtained from Mainland China by HPLC and The classification of the toxicity of traditional Chinese medicines

, 2009
[[abstract]]The purpose of this study was to investigate the present situation of the presence of Aristolochic Acid (AA) in Fangchi or Fangji crude drugs in China after issue of a warning on AA in November 1999.
Shang Hang YU
core  

Detection of aristolochic acid in Chinese phytomedicines and dietary supplements used as slimming regimens

, 2003
Over the last 10 years, numerous cases of intoxications, leading for the most part to end-stage renal failure, have been reported after consumption of slimming regimens made of Chinese herbal preparations. These intoxications were associated with species
Ioset, Jean-Robert, Hostettmann, Kurt, Raoelison, G.E.   +2 more
core   +1 more source