Results 91 to 100 of about 2,520,275 (163)

The epidemiology, diagnosis, and management of aristolochic acid nephropathy: a narrative review.

open access: yes, 2013
It has been 20 years since the first description of a rapidly progressive renal disease that is associated with the consumption of Chinese herbs containing aristolochic acid (AA) and is now termed aristolochic acid nephropathy (AAN).
Schmeiser, Heinz H   +21 more
core   +1 more source

Chemical constituents of Aristolochia rigida Duch and mutagenic activity of aristolochic acid IV

open access: yes, 1993
Two aristolochic acids [2 and 3] and a flavonol glycoside 1 have been isolated from Aristolochia rigida (Aristolochiaceae). Aristolochic acid IV [2], the most abundant constituent, has shown a weak direct mutagenic activity in the Ames test: this action ...
Luisa Pistelli   +9 more
core   +1 more source

Sesquiterpene and Aristolochic Acid Derivatives from Thottea hainanensis

open access: yes, 2010
One new sesquiterpene named thotteodiol (1) with a novel skeleton and one new derivative of aristolochic acid named 7-hydroxyaristolochic acid III methyl ester (2).
Cai, Shao-Qing   +17 more
core   +1 more source

Study on metabolism of plant carcinogen aristolochic acid I

open access: yes, 2019
Aristolochic acids (AA) are natural compounds present in plant species of Aristolochiaceae. These plant alkaloids exhibit nephrotoxic effects and are human carcinogens.
Dedíková, Alena
core  

Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid i in renal tissue from patients with aristolochic acid nephropathy

open access: yes, 2014
Aristolochic acid (AA) causes aristolochic acid nephropathy (AAN), first described in women in Belgium accidently prescribed Aristolochia fangchi in a slimming treatment, and also Balkan endemic nephropathy (BEN), through probable dietary contamination ...
Nortier, Joëlle   +16 more
core   +1 more source

Aristolochic Acid Nephropathy: Molecular Mechanisms, Clinical Impact and Therapeutic Challenges in a Progressive Renal Disease

open access: yesIberoamerican Journal of Medicine
Aristolochic acid nephropathy (AAN) is a rapidly progressive form of interstitial nephritis associated with the use of medicinal plants from the Aristolochiaceae family, which contain aristolochic acid (AA) and environmental pollutants.
Juan José Reinoso-Calle   +2 more
doaj   +1 more source

Review on NMR spectroscopic data and recent analytical methods of aristolochic acids and derivatives in Aristolochia herbs

open access: yesNatural Products and Bioprospecting
Aristolochic acids (AAs) are an important group of secondary metabolites in the genus Aristolochia. The presence of aristolochic acids infers the potency of many Aristolochia herbs used for ages in traditional medicine of China, Europe, Central America ...
Phan Minh Giang   +6 more
doaj   +1 more source

A novel mixed-mode C18SAX stationary phase and the application in the purification of aristolochic acids

open access: yes, 2011
A novel mixed-mode C18SAX stationary phase and the application in the purification of aristolochic ...
魏杰, 章飞芳, 梁鑫淼, 郭志谋
core  

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

open access: yesAdvanced Science
Although significant progress in identifying molecular mediators of fibrosis is made, there is still controversy regarding the role and mechanism of autophagy in kidney fibrosis.
Yan Hu   +11 more
doaj   +1 more source

Growing risk of aristolochic acid nephropathy in the era of COVID-19 - Correspondence. [PDF]

open access: yesInt J Surg, 2022
Das T   +5 more
europepmc   +1 more source

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