Results 81 to 90 of about 2,520,275 (163)
, 2011 Aristolochic acid-I and aristolochic acid-II have been proved to be the main bioactive and toxic component in Aristolochia plants. As a result, the determination of their dissociation constants, which are important property parameters for weak acids, is ...
Xiaofang Fu +11 more
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Nature Communications, 2020 The genomic heterogeneity of clear cell renal cell carcinoma (ccRCC) across populations is poorly understood. Here, the authors analyse a cohort of Chinese ccRCC cases revealing a mutational signature associated with aristolochic acid exposure, and ...
Xiang-Ming Wang +17 more
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An LC/DAD-UV/MS method for the rapid detection of aristolochic acid in plant preparations
, 2002 A new method using direct on-line coupling between HPLC and UV-DAD/MS was developed for the rapid detection of aristolochic acid 1 in plant preparations. The use of both UV-DAD and MS detectors enables this method to be very selective.
Ioset, J.R. +4 more
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miR-192 induces G2/M growth arrest in aristolochic acid nephropathy
, 2014 Aristolochic acid nephropathy is characterized by rapidly progressive tubulointerstitial nephritis culminating in end-stage renal failure and urothelial malignancy.
Davies, Luke C. +9 more
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Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy [PDF]
, 2012 Chinese herbs nephropathy (CHN) and Balkan endemic nephropathy (BEN) are chronic tubulointerstitial renal diseases associated with urothelial carcinoma.
Marc E. De Broe, De Broe, Marc E.
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Anais da Academia Brasileira de Ciências: Aristolochia triangularis Cham., is one of the most frequently used medicinal plant in Southern Brazil. Preparations containing the leaves and/or stems are traditionally used as anti-inflammatory, diuretic, as well as antidote against snakebites.
SIMONE Q. OLIVEIRA +12 more
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ARISTOLACTAMS AND FURTHER CONSTITUENTS FROM ARISTOLOCHIA CHAMISSONIS
Eclética Química, 2018 From the ethanol extract of the stems of Aristolochia chamissonis, spathulenol, sitosterol, b-sitosteryl-D-glucoside, kolavelool, 13-epi-2-oxo-kolavelool, trans-N-p-coumaroyltyramine, allantoin, aristolochic acid I, and aristolactam AII were isolated ...
Angélica Yucari TSURUTA +3 more
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, 2012 Aristolochic acids (AAs), nephrotoxicants and known human carcinogens, are a mixture of structurally related derivatives of nitrophenanthrene carboxylic acids with the major components being aristolochic acid I and aristolochic acid II. People may ingest
CHIANG, SU-YIN;SHIH, WEI-CHUNG;SHU, PO-CHI;HUANG, HEI-FENG;WU, KUEN-YUH +1 more
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Applied SciencesAristolochic acids, compounds derived from Aristolochiaceae plant species, are associated with significant renal nephrotoxicity and carcinogenicity. Aristolochic acid I (AAI), the most predominant and potent of these compounds, is a primary etiological ...
Alexandra T. Lukinich-Gruia +9 more
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Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy
Advances in Pharmacological Sciences, 2011 The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli.
Chiao-Shih Tseng +3 more
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