Results 21 to 30 of about 2,520,275 (163)
Delineation of renal protein profiles in aristolochic acid I-induced nephrotoxicity in mice by label-free quantitative proteomics [PDF]
Introduction: Aristolochic acid nephropathy (AAN) is a kidney injury syndrome caused by aristolochic acids exposure. Our study used label-free quantitative proteomics to delineate renal protein profiles and identify key proteins after exposure to ...
Xinhui Liu +11 more
doaj +2 more sources
Aristolochic acid induces acute kidney injury through ferroptosis [PDF]
Aristolochic acid (AA)-induced acute kidney injury (AKI) presents with progressive decline in renal function and rapid progression to end-stage renal disease.
Xuan Huang +13 more
doaj +2 more sources
Aristolochic Acid Nephropathy: The Hong Kong Perspective [PDF]
Aristolochic acid nephropathy (AAN) is a progressive tubulointerstitial nephropathy attributed to aristolochic acid (AA) toxicity. Five cases of AAN have been diagnosed in Hong Kong.
Poon, Wing-Tat +2 more
core +1 more source
Short-term toxicity of aristolochic acid, aristolochic acid-I and aristolochic acid-II in rats [PDF]
[[abstract]]We compared the short-term toxicity of toxic components of aristolochic acid in rats. Twenty-four female Wistar rats were divided into 4 groups and treated orally every 3-days with 10 mg/kg each of aristolochic acid, aristolochic acid-I and ...
Yen-Hung Yeh;Ya-Ting Lee;Hung-Sheng Hsieh;Deng-Fwu Hwang
core +2 more sources
Aristolochic acids are nephrotoxic and carcinogenic natural products that have been implicated both in endemic nephropathy in the Balkan region and in ailments caused by ingestion of herbal remedies.
J. Martin E. Quirke (2241556) +2 more
core +2 more sources
Interactions of Human Organic Anion Transporters With Aristolochic Acids
Aristolochic acids (AAs), contained in Chinese herbal preparations, have been considered to induce nephropathy. In order to elucidate the molecular mechanisms of AA-induced nephrotoxicity, we have elucidated the interaction of human organic anion ...
Ellappan Babu +8 more
doaj +1 more source
Understanding of the nephrotoxicity induced by drug candidates is vital to drug discovery and development. Herein, an in situ metabolomics method based on air flow-assisted desorption electrospray ionization mass spectrometry imaging (AFADESI-MSI) was ...
Zhonghua Wang +7 more
doaj +1 more source
Aristolochic acid nephropathy - still real danger
Arystolocholic acid nephropathy is chronic kidney disease caused by the use of substances of natural origin that contain arystolocholic acid. The effects of their use are arystolochic acid nephropathies, which include "Chinese Herbs" nephropathy.
Rafal Oleszczuk +4 more
doaj +1 more source
The feeding behaviour of specialist butterflies may be affected by the mechanical and chemical characteristics of the tissues of their host-plants. Larvae of the butterfly, Battus polydamas archidamas feed only on Aristolochia chilensis, which contains ...
Carlos F. PINTO +3 more
doaj +1 more source
Aristolochic acid causes albuminuria by promoting mitochondrial DNA damage and dysfunction in podocyte. [PDF]
Aristolochic acid nephropathy, initially found in patients intaking of slimming herbs containing aristolochic acid (AA), was previously considered as a progressive renal interstitial fibrosis and urothelial malignancy.
Yang Zhou +5 more
doaj +1 more source

