Results 51 to 60 of about 817,904 (149)
Aristolochic acids variation and distribution in some Aristolochia clematitis populations [PDF]
, 1993 Seven wild populations (hypogean and aerial parts) of Aristolochia clematitis, sampling in the North-East Italy, were studied with regard to its aristolochic acids content.
Vrech, Elena +6 more
core
JCI Insight, 2022 Aristolochic acid nephropathy (AAN) is characterized by acute proximal tubule necrosis and immune cell infiltration, contributing to the global burden of chronic kidney disease and urothelial cancer.
Jiayun Chen +10 more
doaj +1 more source
Advanced Science, Volume 13, Issue 30, 28 May 2026.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Acta Biológica Colombiana, 2007 Most butterflies of the tribe Troidini (Lepidoptera: Papilionidae) sequester aristolochic acids (AA) for their protection. These acids are derived from their host plants -family Aristolochiaceae- upon which they feed on during their larval stages.
Ricardo A. Claro +3 more
doaj
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang +13 more
wiley +1 more source
Periodontitis and high phosphate intake alone or in combination adversely affect the kidney
Journal of Periodontology, Volume 97, Issue 5, Page 1026-1037, May 2026.Abstract Background Periodontitis and high phosphate (HP) intake can negatively affect the kidney in the presence of renal disease. This study aimed to evaluate the effects of periodontitis or HP intake, either alone or concurrently, on the periodontal tissue and the kidney under normal renal conditions.
Ae Ri Kim +4 more
wiley +1 more source
Genetic Variation in Chemical Defence Affects Protection of an Herbivorous Insect Against Predation
Molecular Ecology, Volume 35, Issue 9, May 2026.ABSTRACT Genetic variation contributes to intraspecific differences in the chemical defence in many insect species, yet the underlying genetic mechanisms remain poorly understood. The horseradish flea beetle, Phyllotreta armoraciae, sequesters glucosinolates from its horseradish host plant and activates them using endogenous myrosinase enzymes.
Johannes Körnig +9 more
wiley +1 more source
Advanced Science, Volume 13, Issue 19, 2 April 2026.The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan +20 more
wiley +1 more source
Anais da Academia Brasileira de Ciências: Aristolochia triangularis Cham., is one of the most frequently used medicinal plant in Southern Brazil. Preparations containing the leaves and/or stems are traditionally used as anti-inflammatory, diuretic, as well as antidote against snakebites.
SIMONE Q. OLIVEIRA +12 more
doaj +1 more source
Advanced Science, Volume 13, Issue 19, 2 April 2026.Mechanisms of Aristolochic Acid Resistance Why can butterflies feast on toxic Aristolochia plants, while humans are severely harmed by the same toxins? This study unravels the molecular secrets behind the Red‐bodied Swallowtail's resistance to aristolochic acids, offering evolutionary clues to mitigate AA‐associated diseases in humans. More details can
Yang Luan +20 more
wiley +1 more source