Results 111 to 120 of about 4,033 (193)

Tubular CPT1A deletion minimally affects aging and chronic kidney injury

JCI Insight
Kidney tubules use fatty acid oxidation (FAO) to support their high energetic requirements. Carnitine palmitoyltransferase 1A (CPT1A) is the rate-limiting enzyme for FAO, and it is necessary to transport long-chain fatty acids into mitochondria.
Safaa Hammoud, Alla Ivanova, Yosuke Osaki, Steven Funk, Haichun Yang, Olga Viquez, Rachel Delgado, Dongliang Lu, Melanie Phillips Mignemi, Jane Tonello, Selene Colon, Louise Lantier, David H. Wasserman, Benjamin D. Humphreys, Jeffrey Koenitzer, Justin Kern, Mark de Caestecker, Toren Finkel, Agnes Fogo, Nidia Messias, Irfan J. Lodhi, Leslie S. Gewin   +21 more
doaj   +1 more source

Vitamin E (α‑tocopherol) ameliorates aristolochic acid‑induced renal tubular epithelial cell death by attenuating oxidative stress and caspase‑3 activation

, 2017
Tsai‐Kun Wu, Ying‐Ru Pan, Hsueh‐Fang Wang, Chyou‐Wei Wei, Yung‐Luen Yu   +4 more
openalex   +2 more sources

Variation in Presentation and Presence of DNA Adducts and p53 Mutations in Patients with Endemic Nephropathy - an Environmental Form of the Aristolochic Acid Nephropathy [PDF]

, 2013
Sandra Karanović, Ivana Vuković Lela, Bojan Jelaković, Kathleen G. Dickman, Anamarija Kovač Peić, Damir Dittrich, Matej Knežević, Vesna Matijević, A.S. Fernandes, Frederick W. Miller   +9 more
openalex   +1 more source

Mechanisms of DNA repair and mutagenesis induced by acetaldehyde, acrolein, aristolochic acids, and vinyl chloride. [PDF]

J Environ Sci Health C Toxicol Carcinog
Jones K, Dye E, Gilkes N, Xia D, Jiang S, Li W.   +5 more
europepmc   +1 more source

QuEChERS pretreatment combined with high-performance liquid chromatography-tandem mass spectrometry for determination of aristolochic acids I and II in Chinese herbal patent medicines. [PDF]

RSC Adv, 2020
Zhang J, Wang Y, Sun J, Zhou G, Jiang X, Wang X.   +5 more
europepmc   +1 more source

AristoLochic acid I Determination in AristoLochia Clematitis L. raw materials by HPLC Method

, 2020
Lala Pohodina, Nadiia Burda, V. S. Кyslychenko, L. М. Andryukova, Artur Martynov   +4 more
openalex   +1 more source

Pharmacological mechanisms of Fuzheng Huayu formula for Aristolochic acid I–induced kidney fibrosis through network pharmacology

, 2022
Fan Wang, Siyuan Wang, Jing Wang, Kai Huang, Gaofeng Chen, Yuan Peng, Chenghai Liu, Yanyan Tao   +7 more
openalex   +1 more source

Simultaneous Determination of Aristoloxazines, Aristolochic Acids, and Aristolactams Using HPLC-Fluorescence Detection with a Post-column Microreactor: Application in Identifying New Aristoloxazines. [PDF]

J Agric Food Chem
Chin ML, Choi MMF, Tong R, Pavlović NM, Chan W.   +4 more
europepmc   +1 more source

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy

, 2009
Nadiya Bakhiya, Volker M. Arlt, Andrew Bahn, Gerhard Burckhardt, David H. Phillips, Hansruedi Glatt   +5 more
openalex   +2 more sources

Bioactivation mechanisms of N-hydroxyaristolactams: Nitroreduction metabolites of aristolochic acids. [PDF]

Environ Mol Mutagen, 2019
Okuno Y, Bonala R, Attaluri S, Johnson F, Grollman AP, Sidorenko VS, Oda Y.   +6 more
europepmc   +1 more source