Results 101 to 110 of about 817,904 (149)

Molecular mechanism of carcinogenicity of aristolochic acid [PDF]

open access: yes, 2013
Aristolochic acids (AA) are carcinogenic and nephrotoxic alkaloids from Aristolochia species. Aristolochic acid I (AAI), the major component of AA, causes the development of Aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN).
Levová, Kateřina
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Aristolochic Acids, Aristolactam Alkaloids and Amides from Aristolochia Kankauensis

open access: yes, 2009
  Fourteen aristolochic acid derivatives: ariskanins A-E, 3-hydroxy-4- methoxy-10-nitrophenanthrene-1-carboxylic acid methylester, aristolochic acid-II methyl ester, aristolochic acid-IV methylester, aristolochic acid- C, -1, II, -III, IV, -IVa; nine ...
WU, TIEN-SHUNG;OU, LI-FEI;TENG, CHE-MING   +1 more
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Mechanisms of DNA repair and mutagenesis induced by acetaldehyde, acrolein, aristolochic acids, and vinyl chloride. [PDF]

open access: yesJ Environ Sci Health C Toxicol Carcinog
Jones K   +5 more
europepmc   +1 more source

Tubular CPT1A deletion minimally affects aging and chronic kidney injury

open access: yesJCI Insight
Kidney tubules use fatty acid oxidation (FAO) to support their high energetic requirements. Carnitine palmitoyltransferase 1A (CPT1A) is the rate-limiting enzyme for FAO, and it is necessary to transport long-chain fatty acids into mitochondria.
Safaa Hammoud   +21 more
doaj   +1 more source

Study on metabolism of plant carcinogen aristolochic acid I

open access: yes, 2019
Aristolochic acids (AA) are natural compounds present in plant species of Aristolochiaceae. These plant alkaloids exhibit nephrotoxic effects and are human carcinogens.
Dedíková, Alena
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