Results 181 to 190 of about 5,938,973 (323)

Stress-related hypofrontality in depression and its relation to altered activation prior to the stress response. [PDF]

Neuroimage Clin
Int-Veen I, Ehlis AC, Kroczek A, Laicher H, Fallgatter AJ, Rosenbaum D.   +5 more
europepmc   +1 more source

A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF‐07261271 in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim There is an unmet need for more effective therapies in inflammatory bowel disease (IBD). A single drug that blocks multiple distinct pathogenic pathways may offer therapeutic benefit superior to current monotherapies. PF‐07261271, a bispecific antibody targeting both the p40 subunit of interleukin‐12/23 and tumour necrosis factor‐like cytokine 1A ...
Srividya Neelakantan, Christopher Banfield, Kenneth Hung, Anna Sapone, Vivek Pradhan, Yuxi Zhao, Dana Parsons‐Rich, Grace Lee, Bryce G. Johnson, Elena Peeva, Michael S. Vincent, Valerie M. Clerin   +11 more
wiley   +1 more source

Awareness of the relationship between microbiota and exercise: an education-based evaluation. [PDF]

Rev Assoc Med Bras (1992)
Hacioglu O, Ozuberk B, Sakarya S.
europepmc   +1 more source

Effect of esomeprazole on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader, in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this study is to evaluate the effects of multiple doses of esomeprazole, a strong proton pump inhibitor and acid‐reducing agent, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader.
Lana Tran, Naihan Chen, Jennifer A. Winton, Kyle T. Matschke, Smita P. Goodman, Kimberly C. Lee, Yuanyuan Zhang, Weiwei Tan   +7 more
wiley   +1 more source

The role of math anxiety in U.S. adults' ability to metacognitively monitor their fraction arithmetic performance. [PDF]

Front Psychol
Pearl SJ, Thompson CA, Godwin KE, Taber JM, Fitzsimmons CJ.   +4 more
europepmc   +1 more source

Growth mindset is positively associated with mathematics attainment in Scotland—But socioeconomic status plays a greater role

British Educational Research Journal, EarlyView.
Abstract There is currently a gap in knowledge around pupils' growth mindset (GM) and attainment in Scotland, particularly in relation to Socioeconomic Status (SES). This study offers insights on the relevance of growth mindset in Scotland for attainment in mathematics by drawing on large‐scale data from the OECD's Programme for International Student ...
Catherine Reid, Ellen Boeren
wiley   +1 more source

Frailty dimensions and cognitive function in relation to dual-task cost: A multidomain analysis in community-dwelling older adults. [PDF]

J Frailty Aging
Heyzer L, Low K, Tan CN, Yeo A, Chia JQ, Chew J, Kua J, Lim WS.   +7 more
europepmc   +1 more source

Single‐subject designs in character education: Methods for rigorous, contextual, and practitioner‐led research

British Educational Research Journal, EarlyView.
Abstract Character education research is often constrained by blunt methodological tools. Surveys capture breadth without depth; case studies offer richness but lack replicability; and randomised controlled trials (RCTs), though indispensable at the policy level, are costly, disruptive and ill‐suited to everyday practice with individual pupils.
Shane McLoughlin
wiley   +1 more source

Restoration of pre-arthritic coronal alignment improves joint perception following fixed-bearing medial unicompartmental knee arthroplasty. [PDF]

Front Surg
Peng Y, Chen J, Zhao F, Ji G, Zhu C, Liu G.   +5 more
europepmc   +1 more source

Modeling Multiscale Architecture of Biofilm Extracellular Matrix and Its Role in Oxygen Transport

Biotechnology and Bioengineering, EarlyView.
Conceptual ‘resistance‐in‐series' model using cell‐capsule approach is introduced to investigate oxygen transport in the extracellular matrix. Bacterial capsule as a separate, distinct feature from the bulk EPS is the main focus of our present study. ABSTRACT The extracellular polymeric substances (EPS) matrix of microbial biofilms exhibits a complex ...
Raghu K. Moorthy, Eoin Casey
wiley   +1 more source