Results 161 to 170 of about 4,305 (234)

A tale of Rabs and the exocyst complex in ciliary trafficking and biogenesis. [PDF]

Front Cell Dev Biol
Upadhyai P, Bose D, Quadri N.
europepmc   +1 more source

Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies. [PDF]

Commun Med (Lond)
Smith CEL, Streets AJ, Lake AVR, Natarajan S, Best SK, Szymanska K, Karwatka M, Stevenson T, Trowbridge R, Grant G, Grellscheid SN, Foster R, Morrison CG, Mavria G, Bond J, Ong ACM, Johnson CA.   +16 more
europepmc   +1 more source

ARL13B associates with IFT-B complex via IFT46 and IFT74 interactions.

, 2013
Sebiha Cevik, A. W. M. Sanders Anna, Van Wijk Erwin, Karsten Boldt, Lara Clarke, van Reeuwijk Jeroen, Yuji Hori, Nicola Horn, Lisette Hetterschijt, Anita Wdowicz, Andrea Mullins, Kida Katarzyna, I. Kaplan Oktay, E. C. van Beersum Sylvia, Man Wu Ka, J. F. Letteboer Stef, A. Mans Dorus, Toshiaki Katada, Kenji Kontani, Marius Ueffing, Ronald Roepman, Kremer Hannie, Oliver E. Blacque   +22 more
openalex   +1 more source

Ciliopathy-Associated Missense Mutations in IFT140 are Tolerated by the Inherent Resilience of the IFT Machinery. [PDF]

Mol Cell Proteomics
Beyer T, Diwan GD, Leonhard T, Dahlke K, Klose F, Stehle IF, Seda M, Bolz S, Woerz F, Russell RB, Jenkins D, Ueffing M, Boldt K.   +12 more
europepmc   +1 more source

Author response: A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

, 2015
Katja Gotthardt, Mandy Lokaj, Carolin Koerner, Nathalie Falk, Andreas Gießl, Alfred Wittinghofer   +5 more
openalex   +1 more source

A defined tubby domain β-barrel surface region of TULP3 mediates ciliary trafficking of diverse cargoes. [PDF]

Mol Biol Cell
Palicharla VR, Badgandi HB, Hwang SH, Legué E, Liem KF, Mukhopadhyay S.   +5 more
europepmc   +1 more source

Role of Arl13b-exocyst interaction in ciliogenesis

, 2015
Primary cilia are sensory organelles present on nearly every eukaryotic cell. Arl13b belongs to the Arf family of small G proteins. Mutations in this protein were identified in patients with Joubert syndrome, a ciliopathy characterized by neurological defects combined with polydactyly and cystic kidneys.
openaire   +1 more source

Diesel exhaust particle exposure exacerbates ciliary and epithelial barrier dysfunction in the multiciliated bronchial epithelium models

Ecotoxicology and Environmental Safety
Airway epithelium, the first defense barrier of the respiratory system, facilitates mucociliary clearance against inflammatory stimuli, such as pathogens and particulates inhaled into the airway and lung.
Eunsook Park, Bu-Yeo Kim, Seahyoung Lee, Kuk Hui Son, Jihye Bang, Se Hyang Hong, Joong Won Lee, Kyung-Ok Uhm, Hyun-Jeong Kwak, Hyun Joung Lim   +9 more
doaj  

Supplemental Materials and Figure Legends from Arl13b Promotes Gastric Tumorigenesis by Regulating Smo Trafficking and Activation of the Hedgehog Signaling Pathway

, 2023
Jia Shao, Linlin Xu, Limin Chen, Quqin Lu, Xinsheng Xie, Wei Shi, Huanting Xiong, Chao Shi, Xuan Huang, Jinhong Mei, Hai Rao, Hua Lu, Nonghua Lü, Shiwen Luo   +13 more
openalex   +1 more source

A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification. [PDF]

Nat Commun
Wiegering A, Anselme I, Brunetti L, Metayer-Derout L, Calderon D, Thomas S, Nedelec S, Eschstruth A, Serpieri V, Catala M, Antoniewski C, Schneider-Maunoury S, Stedman A.   +12 more
europepmc   +1 more source