Results 161 to 170 of about 2,827 (178)

Dysregulated <i>SASS6</i> expression promotes increased ciliogenesis and cell invasion phenotypes. [PDF]

open access: yesLife Sci Alliance
Hargreaves E   +19 more
europepmc   +1 more source

A type of pancreatic cancer cells form cell clusters from a solitary condition in a primary ciliogenesis-dependent manner. [PDF]

open access: yesMed Mol Morphol
Shirakawa K   +6 more
europepmc   +1 more source
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Arl13b promotes the proliferation, migration, osteogenesis, and mechanosensation of osteoblasts

Tissue and Cell, 2023
Primary cilia are microtubule-based organelles presenting on the surface of most postmitotic mammalian cells. As being signaling hubs and sensory organelles, primary cilia can respond to mechanical and chemical stimuli from the extracellular environment.
Tingting, Lin, Yao, Sun
openaire   +2 more sources

ARL13B promotes angiogenesis and glioma growth by activating VEGFA-VEGFR2 signaling

Neuro-Oncology, 2022
Abstract Background Tumor angiogenesis is essential for solid tumor progression, invasion and metastasis. The aim of this study was to identify potential signaling pathways involved in tumor angiogenesis.
Limin Chen   +12 more
openaire   +2 more sources

PREreview of "Ciliary ARL13B prevents obesity in mice"

2023
This Zenodo record is a permanently preserved version of a PREreview. You can view the complete PREreview at https://prereview.org/reviews/8308506. This review reflects comments and contributions from Femi Arogundade, Elena Sena, Luciana Gallo & Olakunle Jaiyesimi. Review synthesized by Jonny Coates.
Luciana Gallo   +3 more
openaire   +1 more source

A novel Cre‐inducible knock‐in ARL13B‐tRFP fusion cilium reporter

genesis, 2017
SummaryCilia play a major role in the regulation of numerous signaling pathways and are essential for embryonic development. Mutations in genes affecting ciliary function can cause a variety of diseases in humans summarized as ciliopathies. To facilitate the detection and visualization of cilia in a temporal and spatial manner in mouse tissues, we ...
Felizitas Schmitz   +4 more
openaire   +3 more sources

Arl13b controls basal cell stemness properties and Hedgehog signaling in the mouse epididymis

Cellular and Molecular Life Sciences, 2022
Epithelial cells orchestrate a series of intercellular signaling events in response to tissue damage. While the epididymis is composed of a pseudostratified epithelium that controls the acquisition of male fertility, the maintenance of its integrity in the context of tissue damage or inflammation remains largely unknown.
Laura Girardet   +2 more
openaire   +3 more sources

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