Results 31 to 40 of about 2,827 (178)

Identification of Cilia in Different Mouse Tissues

Cells, 2021
Cilia are microtubule-based hair-like organelles that extend from the cell surface. However, the existence and distribution of cilia in each organ and tissue at the postnatal stage in vivo remain largely unknown.
Xinhua Li, Shuting Yang, Vishwa Deepak, Zahra Chinipardaz, Shuying Yang   +4 more
doaj   +1 more source

Loss of zebrafish dzip1 results in inappropriate recruitment of periocular mesenchyme to the optic fissure and ocular coloboma.

PLoS ONE, 2022
Cilia are essential for the development and function of many different tissues. Although cilia machinery is crucial in the eye for photoreceptor development and function, a role for cilia in early eye development and morphogenesis is still somewhat ...
Sri Pratima Nandamuri, Sarah Lusk, Kristen M Kwan   +2 more
doaj   +2 more sources

Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults

Molecular Brain, 2020
Primary cilia are centriole-derived sensory organelles that are present in most mammalian cells, including astrocytes and neurons. Evidence is emerging that astrocyte and neuronal primary cilia demonstrate a dichotomy in the mature mouse brain.
Ashley Sterpka, Juan Yang, Matthew Strobel, Yuxin Zhou, Connor Pauplis, Xuanmao Chen   +5 more
doaj   +1 more source

Dynamics of cilia length in left–right development [PDF]

Royal Society Open Science, 2017
Reduction in the length of motile cilia in the zebrafish left–right organizer (LRO), also known as Kupffer's vesicle, has a large impact on left–right development.
P. Pintado, P. Sampaio, B. Tavares, T. D. Montenegro-Johnson, D. J. Smith, S. S. Lopes   +5 more
doaj   +1 more source

Palmitoylation of acetylated tubulin and association with ceramide-rich platforms is critical for ciliogenesis

Journal of Lipid Research, 2021
: Microtubules are polymers composed of αβ-tubulin subunits that provide structure to cells and play a crucial role in in the development and function of neuronal processes and cilia, microtubule-driven extensions of the plasma membrane that have sensory
Priyanka Tripathi, Zhihui Zhu, Haiyan Qin, Ahmed Elsherbini, Simone M. Crivelli, Emily Roush, Guanghu Wang, Stefka D. Spassieva, Erhard Bieberich   +8 more
doaj   +1 more source

Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain. [PDF]

PLoS Genetics, 2013
Cilia are microtubule-based cell appendages, serving motility, chemo-/mechano-/photo- sensation, and developmental signaling functions. Cilia are comprised of distinct structural and functional subregions including the basal body, transition zone (TZ ...
Sebiha Cevik, Anna A W M Sanders, Erwin Van Wijk, Karsten Boldt, Lara Clarke, Jeroen van Reeuwijk, Yuji Hori, Nicola Horn, Lisette Hetterschijt, Anita Wdowicz, Andrea Mullins, Katarzyna Kida, Oktay I Kaplan, Sylvia E C van Beersum, Ka Man Wu, Stef J F Letteboer, Dorus A Mans, Toshiaki Katada, Kenji Kontani, Marius Ueffing, Ronald Roepman, Hannie Kremer, Oliver E Blacque   +22 more
doaj   +1 more source

Defective hippocampal astrocyte and neuronal primary cilia function in offspring brain of pregnant rats with advanced age might be associated with promoting apoptosis through LKB1/AMPK pathway

陆军军医大学学报, 2023
Objective Objective To investigate the changes in hippocampal astrocytes and neuronal primary cilia, and neuronal apoptosis in the offspring brain of advanced maternal age and the role of LKB1/AMPK pathway.
HAN Ziyao, LUO Hanyu, GUI Jianxiong, YUAN Ping, JIANG Li   +4 more
doaj   +1 more source

DRES-02. CILIARY PROTEIN ARL13B PROMOTES CHEMORESISTANCE BY MODULATE GLIOBLASTOMA PURINE BIOSYNTHESIS [PDF]

Neuro-Oncology, 2018
Jack Shireman, Fatemeh Atashi, Cheol Park, Louisa Warnke, Jason Miska, Atique U. Ahmed   +5 more
openalex   +2 more sources

Decision letter: ARL13B regulates Sonic hedgehog signaling from outside primary cilia

, 2019

openalex   +2 more sources

Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration

eLife, 2023
The small GTPase Arl3 is important for the enrichment of lipidated proteins to primary cilia, including the outer segment of photoreceptors. Human mutations in the small GTPase Arl3 cause both autosomal recessive and dominant inherited retinal ...
Amanda M Travis, Samiya Manocha, Jason R Willer, Timothy S Wessler, Nikolai P Skiba, Jillian N Pearring   +5 more
doaj   +1 more source