Results 51 to 60 of about 3,974 (218)
Ciliary ARL13B prevents obesity in mice
, 2023 AbstractCilia are near ubiquitous small, cellular appendages critical for cell-to-cell communication. As such, they are involved in diverse developmental and homeostatic processes, including energy homeostasis. ARL13B is a regulatory GTPase highly enriched in cilia.
Tiffany T. Terry +8 more
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繊毛タンパク質の局在機構および繊毛病の分子基盤の解析 [PDF]
, 2021 京都大学新制・課程博士博士(薬科学)甲第23474号薬科博第144号新制||薬科||16(附属図書館)京都大学大学院薬学研究科薬科学専攻(主査)教授 中山 和久, 教授 井垣 達吏, 教授 土居 雅夫学位規則第4条第1項該当Doctor of Pharmaceutical SciencesKyoto ...
QIU, HANTIAN
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PLoS ONE, 2022 Cilia are essential for the development and function of many different tissues. Although cilia machinery is crucial in the eye for photoreceptor development and function, a role for cilia in early eye development and morphogenesis is still somewhat ...
Sri Pratima Nandamuri +2 more
doaj +2 more sources
Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults
Molecular Brain, 2020 Primary cilia are centriole-derived sensory organelles that are present in most mammalian cells, including astrocytes and neurons. Evidence is emerging that astrocyte and neuronal primary cilia demonstrate a dichotomy in the mature mouse brain.
Ashley Sterpka +5 more
doaj +1 more source
Arl13b influences cilia length in the zebrafish Kupffer’s vesicle [PDF]
Cilia, 2013 Joubert Syndrome is a ciliopathy that can be caused by a mutation in Arl13b protein. This syndrome is characterized by problems in embryonic development, especially at the neurological level. Arl13b is a protein that belongs to the small GTPase family, but presents the double size of a normal GTPase, because it has a different C-terminus with a coiled ...
Duarte C. Barral +2 more
openaire +2 more sources
Dynamics of cilia length in left–right development [PDF]
Royal Society Open Science, 2017 Reduction in the length of motile cilia in the zebrafish left–right organizer (LRO), also known as Kupffer's vesicle, has a large impact on left–right development.
P. Pintado +5 more
doaj +1 more source
陆军军医大学学报, 2023 Objective Objective To investigate the changes in hippocampal astrocytes and neuronal primary cilia, and neuronal apoptosis in the offspring brain of advanced maternal age and the role of LKB1/AMPK pathway.
HAN Ziyao +4 more
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Tumor Treating Fields Suppression of Ciliogenesis Enhances Temozolomide Toxicity
Frontiers in Oncology, 2022 Tumor Treating Fields (TTFields) are low-intensity, alternating intermediate-frequency (200 kHz) electrical fields that extend survival of glioblastoma patients receiving maintenance temozolomide (TMZ) chemotherapy.
Ping Shi +8 more
doaj +1 more source
PREreview of "Ciliary ARL13B prevents obesity in mice"
, 2023 This Zenodo record is a permanently preserved version of a PREreview. You can view the complete PREreview at https://prereview.org/reviews/8308506. This review reflects comments and contributions from Femi Arogundade, Elena Sena, Luciana Gallo & Olakunle Jaiyesimi. Review synthesized by Jonny Coates.
Luciana Gallo +3 more
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ARL3 mutations cause Joubert syndrome by disrupting ciliary protein composition [PDF]
, 2018 Joubert syndrome (JBTS) is a genetically heterogeneous autosomal recessive neurodevelopmental ciliopathy. We investigated further the underlying genetic etiology of Joubert syndrome by studying two unrelated families in whom JBTS was not associated ...
Alhashem, Amal +18 more
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