Results 71 to 80 of about 120,360 (287)

Impact of motor task conditions on end-point kinematics and trunk movements during goal-directed arm reach

open access: yesScientific Reports
Task conditions significantly impact human motor control. We investigated how task type, difficulty, and constraints influence the kinematics of goal-directed arm reaching. Non-disabled young adults performed two distinct goal-directed arm reaching tasks:
Bokkyu Kim   +5 more
doaj   +1 more source

Effects of Rhythmic Auditory Stimulation During Hemiplegic Arm Reaching in Individuals with Stroke: An Exploratory Study

open access: yesHong Kong Journal of Occupational Therapy, 2014
Objective/Background: This study investigated the effects of rhythmic auditory stimulation (RAS) on muscle activity and elbow motion during arm reaching with hemiplegic arm in participants with stroke. Methods: Sixteen adults with stroke who resided in a
Jung-ran Kim   +5 more
doaj   +1 more source

Double-Step Paradigm in Microgravity: Preservation of Sensorimotor Flexibility in Altered Gravitational Force Field

open access: yesFrontiers in Physiology, 2020
The way we can correct our ongoing movements to sudden and unforeseen perturbations is key to our ability to rapidly adjust our behavior to novel environmental demands.
L. Bringoux   +8 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Accuracy deficits during robotic time-constrained reaching are related to altered prefrontal cortex activity in children with cerebral palsy

open access: yesJournal of NeuroEngineering and Rehabilitation
Background The prefrontal cortex (PFC) is an important node for action planning in the frontoparietal reaching network but its role in reaching in children with cerebral palsy (CP) is unexplored.
Owais A. Khan   +3 more
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

On singular values decomposition and patterns for human motion analysis and simulation [PDF]

open access: yes, 2012
We are interested in human motion characterization and automatic motion simulation. The apparent redun- dancy of the humanoid w.r.t its explicit tasks lead to the problem of choosing a plausible movement in the framework of redun- dant kinematics.
Chiron, Pascale   +5 more
core   +1 more source

Reconstruction of reaching movement trajectories using electrocorticographic signals in humans. [PDF]

open access: yesPLoS ONE, 2017
In this study, we used electrocorticographic (ECoG) signals to extract the onset of arm movement as well as the velocity of the hand as a function of time.
Omid Talakoub   +6 more
doaj   +1 more source

Coordination of arm and wrist motion during a reaching task [PDF]

open access: yesThe Journal of Neuroscience, 1982
An analysis of arm movements involving forward projection of the hand in order to reach for and grasp a target at different orientations is presented. The reaching movements required shoulder flexion, elbow extension, and wrist pronation or supination.
LACQUANITI, FRANCESCO, Soechting, JF
openaire   +3 more sources

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