Results 71 to 80 of about 1,061,568 (282)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Reconstruction of reaching movement trajectories using electrocorticographic signals in humans. [PDF]
PLoS ONE, 2017 In this study, we used electrocorticographic (ECoG) signals to extract the onset of arm movement as well as the velocity of the hand as a function of time.
Omid Talakoub +6 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Quantitative evaluation of muscle synergy models: a single-trial task decoding approach
Frontiers in Computational Neuroscience, 2013 Muscle synergies, i.e. invariant coordinated activations of groups of muscles, have been proposed as building blocks that the central nervous system uses to construct the patterns of muscle activity utilized for executing movements.
Ioannis eDelis +8 more
doaj +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Differential Recruitment of Parietal Cortex during Spatial and Non-spatial Reach Planning
Frontiers in Human Neuroscience, 2017 The planning of goal-directed arm reaching movements is associated with activity in the dorsal parieto-frontal cortex, within which multiple regions subserve the integration of arm- and target-related sensory signals to encode a motor goal. Surprisingly,
Pierre-Michel Bernier +2 more
doaj +1 more source
Simultaneous bilateral training for improving arm function after stroke [PDF]
, 2009 Background Simultaneous bilateral training, the completion of identical activities with both arms simultaneously, is one intervention to improve arm function and reduce impairment.
Morris, J. +12 more
core +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Deep Reinforcement Learning-Based Enhancement of Robotic Arm Target-Reaching Performance
ActuatorsThis work investigates the implementation of the Deep Deterministic Policy Gradient (DDPG) algorithm to enhance the target-reaching capability of the seven degree-of-freedom (7-DoF) Franka Pandarobotic arm.
Ldet Honelign +3 more
doaj +1 more source
Frontiers in Human Neuroscience, 2010 Motor control and adaptation are multi-determinate processes with complex interactions. This is reflected for example in the ambiguous nature of interactions during sequential adaptation of reaching under kinematics and dynamics perturbations.
Fritzie Arce +4 more
doaj +1 more source