Results 61 to 70 of about 120,360 (287)
When ears drive hands: the influence of contact sound on reaching to grasp [PDF]
, 2010 <b>Background</b> Most research on the roles of auditory information and its interaction with vision has focused on perceptual performance. Little is known on the effects of sound cues on visually-guided hand movements.<p></p>
Ansuini Caterina +21 more
core +1 more source
The FASEB Journal, 2006 Reaching towards a bionic arm The biggest challenge for a bionic arm is to communicate effectively with its user. My laboratory has developed new communication tools that allow prospective users of a bionic arm to regain proportional control over several movements of the hand, thus restoring a degree of dexterity.
openaire +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
THE EFFECT OF THE MYOMO ROBOTIC ORTHOSIS ON REACH PERFORMANCE AFTER STROKE [PDF]
, 2013 Stroke affects 795,000 people yearly. Close to 85 percent of stroke survivors experience some degree of stroke-related upper extremity impairment due to spastic paresis (Nakayama, Jorgenson, Pedersen, Raaschou, & Olsen, 1994).
Bleakley, Scott
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Developmental Cognitive Neuroscience, 2015 Previous studies have shown that sensorimotor cortex activation is somatotopically-organised during action execution and observation in adulthood. Here we aimed to investigate the development of this phenomenon in infancy. We elicited arm and leg actions
Carina C.J.M. de Klerk +2 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Tasks of daily life require the independent use of the arms and hands. Individuals with hemiparetic cerebral palsy (HCP) often experience difficulty with fine motor tasks demonstrating mirrored movements between the arms.
Nayo M. Hill +6 more
doaj +1 more source
Patterns of Arm Muscle Activation Involved in Octopus Reaching Movements
, 1998 The extreme flexibility of the octopus arm allows it to perform many different movements, yet octopuses reach toward a target in a stereotyped manner using a basic invariant motor structure: a bend traveling from the base of the arm toward the tip ...
Graziano Fiorito +3 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source