Results 51 to 60 of about 570,610 (284)
Spatial eye–hand coordination during bimanual reaching is not systematically coded in either LIP or PRR [PDF]
, 2018 Significance When we reach for something, we also look at it. If we reach for two objects at once, one with each hand, we look first at one and then the other. It is not known which brain areas underlie this coordination.
Mooshagian, Eric, Snyder, Lawrence H.
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Effect of Tendon Vibration on Hemiparetic Arm Stability in Unstable Workspaces [PDF]
, 2015 Sensory stimulation of wrist musculature can enhance stability in the proximal arm and may be a useful therapy aimed at improving arm control post-stroke.
Conrad, Megan O. +3 more
core +4 more sources
The FASEB Journal, 2006 Reaching towards a bionic arm The biggest challenge for a bionic arm is to communicate effectively with its user. My laboratory has developed new communication tools that allow prospective users of a bionic arm to regain proportional control over several movements of the hand, thus restoring a degree of dexterity.
openaire +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Journal of NeuroEngineering and Rehabilitation, 2006 Background and purpose Providing active assistance to complete desired arm movements is a common technique in upper extremity rehabilitation after stroke.
Rymer W Zev +3 more
doaj +1 more source
Effects of Wrist Tendon Vibration on Targeted Upper-Arm Movements in Poststroke Hemiparesis [PDF]
, 2011 Background. Impaired motor control of the upper extremity after stroke may be related to lost sensory, motor, and integrative functions of the brain. Artificial activation of sensory afferents might improve control of movement by adding excitatory drive ...
Conrad, Megan O. +2 more
core +1 more source
Inter-Joint Coordination Deficits Revealed in the Decomposition of Endpoint Jerk During Goal-Directed Arm Movement After Stroke [PDF]
, 2017 It is well documented that neurological deficits after stroke can disrupt motor control processes that affect the smoothness of reaching movements.
Laczko, Jozsef +3 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source