Results 61 to 70 of about 34,191 (252)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Legal Adaptation of Internationalized Armed Conflict [PDF]
الرافدین للحقوقArmed conflicts are the milestone in the history of international relations, and since the concept of armed conflict in the past is different from what it is today, , has begun to talk about a new concept is In the term armed conflict, finding legal ...
Abdul Aziz kashumula, Abdulaziz Alkitaby
doaj +1 more source
Change in armed conflict: An introduction
International Political Science Review, 2023 How can we understand change in armed conflict, both in terms of the phenomenon as a whole, as well as within individual conflicts? This Special Issue sets a new agenda on the theme of change in armed conflict. Studying conflict as a dynamic social phenomenon requires embracing interdisciplinarity and methodological pluralism, which this Special Issue ...
openaire +2 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The surprising decline of international mediation in armed conflicts
Research & Politics, 2020 We identify and investigate a fundamental puzzle in contemporary mediation of armed conflicts. Although the preparedness of international mediators has increased, the proportion of armed conflicts that receive mediation has not increased, but decreased ...
Magnus Lundgren, Isak Svensson
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Future armed conflicts - A new point of view [version 2; peer review: 2 approved]
Stosunki MiędzynarodoweThis article focusses on future wars and the resulting consequences for the development of the armed forces. The purpose of this study is to indicate the course of future armed conflicts on the base of the forecasts presented by the largest research ...
Tomasz Smal +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source