Results 71 to 80 of about 51,536 (297)

AN OVERVIEW OF THE GENESIS, SOURCES, MANIFESTATIONS AND IMPACT OF SMALL ARMS AND LIGHT WEAPONS (SALW) IN NORTHERN NIGERIA

open access: yesJournal of International Studies, 2020
The protracted proliferation of Small Arms and Light Weapons (SALW) from around the globe to Africa, specifically in Northern Nigeria, had led to a plethora of social crises that have culminated to the insecurity across the region for more than a decade.
Babayo Sule   +2 more
doaj   +3 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Armed Conflicts, 1946—2009

open access: yes, 2010
In 2009, UCDP recorded 36 active armed conflicts, down by one from 2008. Having remained fairly stable over the past few years, the number of armed conflicts is now substantially lower than during the peak years of the early 1990s.
Lotta Harbom, Peter Wallensteen
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Spatiotemporal Evolution of Armed Conflicts in Africa and the Risk Characteristics to China's Overseas Interests

open access: yesRedai dili
With the advancement of the "Belt and Road" initiative, China's investment in Africa has increased steadily in recent years, and trade volume has expanded continuously. However, due to the frequent occurrence of armed conflicts in Africa, the security of
Pi Shuaishuai, Ba Rui, Yang Xuan
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Change in armed conflict: An introduction

open access: yesInternational Political Science Review, 2023
How can we understand change in armed conflict, both in terms of the phenomenon as a whole, as well as within individual conflicts? This Special Issue sets a new agenda on the theme of change in armed conflict. Studying conflict as a dynamic social phenomenon requires embracing interdisciplinarity and methodological pluralism, which this Special Issue ...
openaire   +2 more sources

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Future armed conflicts - A new point of view [version 2; peer review: 2 approved]

open access: yesStosunki Międzynarodowe
This article focusses on future wars and the resulting consequences for the development of the armed forces. The purpose of this study is to indicate the course of future armed conflicts on the base of the forecasts presented by the largest research ...
Tomasz Smal   +2 more
doaj   +1 more source

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