Results 41 to 50 of about 291,608 (311)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Genocidas ir Rezistencija, 2012 The article analyses the Thorn Company, a partisan unit that operated in northeast Lithuania, and the link of its partisans with the previously established societal tradition of self-defence and armed activity.
Dainius Noreika
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Genocidas ir Rezistencija, 2011 The post-war guerrilla warfare in Lithuania was nothing new since the traditions of the guerrilla movement dated back to the 1919–1923 battles for independence and confrontations with Polish forces in the neutral territory.
Vytautas Jokubauskas
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Some Features of the Lithuanian Resistance Phenomenon
Genocidas ir Rezistencija, 2003 Speaking presently about the post-war resistance, it is already possible to refer to authentic documentation, which allows analysis of the political and ideological features of the resistance.
Arvydas Anušauskas
doaj +1 more source
spotlight europe #2013/02-February 2012. Syria: from rebellion to all-out war [PDF]
, 2013 The situation in Syria at the beginning of 2013 could hardly be worse. Dead, wounded, refugees, a humanitarian disaster. President Assad is destroying his country and waging war against his own people. Russia and Iran back the regime.
Hanelt, Christian-P., Helberg, Kristin
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
NKVD kariuomenės dokumentai Rusijos karo archyve
Genocidas ir Rezistencija, 1997 Historians studying the armed struggle against the Soviet invaders in 1944–1953 are constantly confronted with the problem of identifying the military structures of occupation.
Arvydas Anušauskas
doaj +1 more source
Beyond collective violence: capturing context and complexity in Palestinian diasporic resistance [PDF]
, 2017 Approximately 50 percent of the world’s Palestinians reside in the diaspora, territorially disconnected from occupied Palestine, but no less part of a population so often associated with political resistance.
Harris, Scarlet
core +1 more source