Results 51 to 60 of about 2,382,973 (247)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Research of the possibilities of armed resistance. [PDF]

open access: yes, 2019
In case of the occupation, citizens of the Republic of Lithuania must know how to resist or to continue fight the occupants. Every citizen can take a part in activities, which are harmful to the enemy or helpful for active participants of the resistance.
Lukša, Gediminas,
core   +1 more source

NKVD kariuomenės dokumentai Rusijos karo archyve

open access: yesGenocidas ir Rezistencija, 1997
Historians studying the armed struggle against the Soviet invaders in 1944–1953 are constantly confronted with the problem of identifying the military structures of occupation.
Arvydas Anušauskas
doaj   +1 more source

On Government-industry Nexus and Indigenous Armed Resistance [PDF]

open access: yesDefence and Peace Economics, 2017
AbstractThis paper proposes a simple game-theoretic framework for analyzing the relationship between the government, industry and indigenous community, especially in the context of mounting violence surrounding displacement of indigenous communities by governments for the purposes of commercial use of their habitat.
openaire   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The Activities of NKVD Forces of Rear Defence Fronts in Lithuania (1944–1945)

open access: yesGenocidas ir Rezistencija, 1997
This is an article on the NKVD army of the 3rd Belarusian background front and is a fragment of a paper on those Soviet military occupying forces (rifle regiments, border regiments and detachments, destruction battalions made up of collaborators) that ...
Juozas Starkauskas
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A role played by the All-Union Communist Party (Bolsheviks) Central Committee Bureau for Lithuania in suppressing resistance of partisans (November 1944–March 1947)

open access: yesGenocidas ir Rezistencija, 2017
The article examines the role of one of the main administrative institutions of the Soviet occupation, the All-Union Communist Party (Bolsheviks) Central Committee Bureau for Lithuanian Affairs, in organising the suppression of the anti-Soviet ...
Mindaugas Pocius
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Distinguish between terrorism and legitimate armed resistance

open access: yes, 2023
<p>When studying terrorist crime, it is natural to distinguish it from other forms of criminal behavior that may be mixed with it in order to determine the true magnitude of that phenomenon, which leads to distinguishing the terrorist from the ...
mostafa elokaby
core   +1 more source

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