Results 71 to 80 of about 29,080 (334)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Genocidas ir Rezistencija, 2017 The article examines the role of one of the main administrative institutions of the Soviet occupation, the All-Union Communist Party (Bolsheviks) Central Committee Bureau for Lithuanian Affairs, in organising the suppression of the anti-Soviet ...
Mindaugas Pocius
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Overexpression of Smac by an Armed Vesicular Stomatitis Virus Overcomes Tumor Resistance
Molecular Therapy: Oncolytics, 2019 Despite reports of successful clinical cases, many tumors appear to resist infection by oncolytic viruses (OVs). To circumvent this problem, an armed vesicular stomatitis virus was constructed by inserting a transgene to express Smac/DIABLO during virus ...
Weike Li +11 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
Gender (in)equality within the Swedish Armed Forces : Resistance and Functional Disinclination [PDF]
, 2023 Historically and traditionally, military work has been closely associated with men. However, the post-Cold War normalization process has brought about a transformation in both the Swedish Armed Forces themselves and the perception of the organization ...
Linehagen, Frida
core +1 more source
Genocidas ir Rezistencija, 2019 Although “the life of Salomėja Nėris is better documented than that of any other Lithuanian woman (and better than that of any other writer)”, this is far from meaning that everything is known about her biography.
Mingailė Jurkutė
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Genocidas ir Rezistencija, 2013 Culture, spiritual and moral values are an inexhaustible source that for centuries revived the Lithuanian nation and gave it the strength to fight against all those who tried to destroy its statehood and suppress its aspirations for freedom.
Juozapas Romualdas Bagušauskas
doaj +1 more source