Results 41 to 50 of about 2,382,973 (247)

Understanding effects of armed conflict on health outcomes: the case of Nepal [PDF]

open access: yes, 2010
Objective There is abundance of literature on adverse effects of conflict on the health of the population. In contrast to this, sporadic data in Nepal claim improvements in most of the health indicators during the decade-long armed conflict (1996-2006).
van Teijlingen Edwin R   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Armed resistance of partisans in 1944–1953 and its suppression in Skapiškis rural district

open access: yesGenocidas ir Rezistencija, 2018
There were similarities and differences between armed resistance activities of partisans that took place in various regions of Lithuania in 1944–1953. Still, irrespective of several regional peculiarities, three main periods of the partisan warfare may ...
Ramona Staveckaitė-Notari
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

From Lithuanian Riflemen to Forest Brothers: Research on the Development of the Local Military Structure

open access: yesGenocidas ir Rezistencija, 2012
The article analyses the Thorn Company, a partisan unit that operated in northeast Lithuania, and the link of its partisans with the previously established societal tradition of self-defence and armed activity.
Dainius Noreika
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Epsilon–First Policies for Budget–Limited Multi-Armed Bandits

open access: yes, 2010
We introduce the budget–limited multi–armed bandit (MAB), which captures situations where a learner’s actions are costly and constrained by a fixed budget that is incommensurable with the rewards earned from the bandit machine, and then describe a first ...
Tran-Thanh, Long   +4 more
core   +2 more sources

Looking into the Future: the Spread and Realization of Guerrilla Warfare Tactics in Lithuania in 1944–1953

open access: yesGenocidas ir Rezistencija, 2011
The post-war guerrilla warfare in Lithuania was nothing new since the traditions of the guerrilla movement dated back to the 1919–1923 battles for independence and confrontations with Polish forces in the neutral territory.
Vytautas Jokubauskas
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Some Features of the Lithuanian Resistance Phenomenon

open access: yesGenocidas ir Rezistencija, 2003
Speaking presently about the post-war resistance, it is already possible to refer to authentic documentation, which allows analysis of the political and ideological features of the resistance.
Arvydas Anušauskas
doaj   +1 more source

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