Results 31 to 40 of about 1,843 (294)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The medieval inventories of the Tower armouries 1320–1410 [PDF]
This research project arose from the need to provide an edition of the manuscript inventories of the privy wardrobe at the Tower. Though these are an important source for the study of arms and armour during the first half of the Hundred Years War only ...
Richardson, R T
core
Not armour, but biomechanics, ecological opportunity and increased fecundity as keys to the origin and expansion of the mineralized benthic metazoan fauna [PDF]
This paper offers a new biotic interaction hypothesis for the Cambrian 'explosion' of mineralized, benthic, metazoan diversity. It proposes that organic-mineral composite structures (e.g.
Cohen, B.L.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The failure of a tungsten carbide-cobalt cored projectile penetrating a hard target [PDF]
Experimental results are presented from an investigation of the parameters of a ceramic-faced armour system that are required to induce damage in a tungsten carbide - cobalt (WC-Co) penetrator.
Woolmore, Nicola J.
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Um modelo de espada criado pelos portugueses na primeira metade do século XV?
Up until now, all international arms and armour specialists have considered that swords with double guard were created in Iberia in the end of 15th century and used till the middle of 16th century.
Henrique Seruca, Mário Jorge Barroca
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Armour and Arms in Shakespeare [PDF]
(1908). Armour and Arms in Shakespeare. Archaeological Journal: Vol. 65, No. 1, pp. 270-281.
openaire +2 more sources

