Results 51 to 60 of about 40,518 (302)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Reaching Excellence: Staff Weapon Typologies, Contexts, and Fighting Techniques in the Collectanea of Pietro Monte

open access: yesActa Periodica Duellatorum, 2019
The sixteenth-century Collectanea of the condottiero Pietro Monte contains some of the most thorough writings that exist pertaining to the use of staff weapons.
Deacon Jacob Henry   +1 more
doaj   +1 more source

General Simonds Speaks: Canadian Battle Doctrine in Normandy [PDF]

open access: yes, 2012
On the afternoon of 11 July 1944, a Canadian Corps HQ once again became operational on the soil of France. Lieutenant-General Guy Granville Simonds assumed responsibility for 8,000 yards of front in the Caen sector.
Copp, Terry, Simonds, Guy
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

'Always the foremost argive champion'? The representation of Neoptolemus in Quintus of Smyrna's posthomerica [PDF]

open access: yes, 2015
Neoptolemus rather seldom figures in Ancient Greek literature. The Posthomerica of Quintus of Smyrna is one of the scarce examples in which the son of Achilles is staged as a hero on the battlefield.
Scheijnen, Tine
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

“The Bosporan Army” and “The Army on the Bosporus” in the time of Mithradates VI Eupator, King of Pontus

open access: yesFasciculi Archaeologiae Historicae, 2014
During the reign of Mithradates VI Eupator, king of Pontus, the Cimmerian Bosporus was incorporated to the kingdom of Pontus. Detachments of the Mithradatic army were located on the Bosporus.
Mariusz Mielczarek
doaj  

New Rulers, New Rules?

open access: yesFasciculi Archaeologiae Historicae, 2020
This paper discusses problems of changes in military equipment that was in use in the historical Sanok Land. Being situated in the borderland of Piast Poland and the Halych-Volhynia Principality, Sanok was located at the interface of two civilisations –
Piotr N. Kotowicz, Paweł Skowroński
doaj   +1 more source

“Monty’s Functional Doctrine: Combined Arms Doctrine in British 21st Army Group in Northwest Europe, 1944-45 (Book Review)” by Charles Forrester. [PDF]

open access: yes, 2017
Review of Monty’s Functional Doctrine: Combined Arms Doctrine in British 21st Army Group in Northwest Europe, 1944-45 by Charles ...
Stubbs, David
core   +1 more source

The physical structure of the point-symmetric and quadrupolar planetary nebula NGC 6309

open access: yes, 2008
We analyse the point-symmetric planetary nebula NGC 6309 in terms of its three-dimensional structure and of internal variations of the physical conditions to deduce the physical processes involved in its formation.
Amnuel   +54 more
core   +1 more source

Home - About - Disclaimer - Privacy