Results 31 to 40 of about 398,162 (307)

Sino-Soviet relations, 1964-1965 [PDF]

open access: yes, 1965
"Prepared for the Conference on Sino-Soviet Relations and Arms Control sponsored by Harvard University under contract with the Arms Control and Disarmament Agency, Airlie House, Warrenton, Virginia, August 30-September 4, 1965.""1596"--handwritten on ...
Griffith, William E.   +1 more
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Irreversibility in Nuclear Arms Control: Lessons from the US-Soviet/Russian Arms Control Process

open access: yesJournal for Peace and Nuclear Disarmament
The United States and Soviet Union/Russian Federation signed several arms control treaties that mandated reductions in their numbers of deployed nuclear weapons.
Amy F. Woolf
doaj   +1 more source

Fault Lines between East and West: Which Levers Can Rebuild Confidence?

open access: yesJournal for Peace and Nuclear Disarmament, 2020
Several regional fault lines will define the character of relations between East and West in the coming years. It is already evident that notably in the Baltic region, both NATO and Russia have squandered a great deal of confidence, which will have to be
Nadja Douglas
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Developing Russia–NATO relations: problemsof arms control and limitations on destabilizing military activities of the Alliance

open access: yesМеждународная аналитика, 2016
The article is devoted to some critical aspects of correspondence of the Alliance status to the basic norms of international law. It also centers on specific actual steps of the realization of the NATO long-term strategy of «openness» in interrelations ...
I. Kuznetsov
doaj   +1 more source

Changes in International Arms Control and China’s Role

open access: yesChina Quarterly of International Strategic Studies, 2020
The international arms control regime has arrived at a crossroads as the United States pulls out of a number of international treaties and launches a new round of defense and military buildup in pursuit of absolute strategic and technological superiority.
Chunsi Wu
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Firing blanks? The Arms Trade Treaty [PDF]

open access: yes, 2014
This paper assesses key provisions of the ATT by first back-grounding its origins and contested formulation before assessing its transfer, prohibition and national control provisions, Introduction The Arms Trade Treaty (ATT) was adopted by vote at the ...
Roderic Alley
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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