Results 41 to 50 of about 9,934,301 (252)

Arms control negotiations : United States-Soviet treaties

open access: yes, 1984
In 1984 President Ronald Reagan, acting in response to congressional inquiries, presented a detailed study of Soviet noncompliance with arms control treaties.
Krogh, Peter F. (Peter Frederic)
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Economic factors and Soviet arms control policy : the economic burden of the Soviet defense effort

open access: yes, 1964
"November 2, 1964."Series numbering changed on cover and t.p. by the Center"1560"--handwritten on coverIncludes bibliographical referencesPrepared under a contract with the U.S.
Ermarth, Fritz Walter, 1941-
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Assessing emerging technologies from an arms control perspective. [PDF]

open access: yesFront Res Metr Anal, 2022
Brackmann M   +3 more
europepmc   +1 more source

Future of arms control after the Reykjavik Summit; Arms control after the Summit

open access: yes, 1986
Since the beginning of the atomic age, fear of nuclear destruction has hung over all the nations of the earth. This fear had the potential of being reduced after significant talks at the Reykjavik Summit between President Reagan and Premier Mikhail ...
Krogh, Peter F. (Peter Frederic)
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Crisis in arms control: an introduction. [PDF]

open access: yesZ Friedens Konfliktforsch, 2021
Wisotzki S, Kühn U.
europepmc   +1 more source

What to do about Soviet arms control violations

open access: yes, 1986
From the Geneva Convention banning chemical weapons up through the SALT treaties, the idea of controlling the world’s armaments to prevent war was popular throughout the twentieth century. Over the course of the cold war, U.S. and Soviet efforts to limit
Krogh, Peter F. (Peter Frederic)
core  

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