Results 41 to 50 of about 15,875,601 (337)

Mad Momentum Redux? The Rise and Fall of Nuclear Arms Control

open access: yesSurvival: Global Politics and Strategy, 2019
Legacy Cold War-era arms control is collapsing and a nuclear arms race is threatening to return.
A. Arbatov
semanticscholar   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher   +8 more
wiley   +1 more source

Developing Russia–NATO relations: problemsof arms control and limitations on destabilizing military activities of the Alliance

open access: yesМеждународная аналитика, 2016
The article is devoted to some critical aspects of correspondence of the Alliance status to the basic norms of international law. It also centers on specific actual steps of the realization of the NATO long-term strategy of «openness» in interrelations ...
I. Kuznetsov
doaj   +1 more source

Strategic Stability: Dynamics and Factors of Transformation

open access: yesВестник Московского Университета. Серия XXV: Международные отношения и мировая политика, 2023
The paper provides a comparative analysis study of the dynamics and mechanisms of the strategic stability transformation both during the Cold War and at present.
K. V. Bogdanov
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Contemplating a Cyber Weapons Convention: An Exploration of Good Practice and Necessary Preconditions

open access: yesBaltic Journal of Law & Politics, 2020
Despite being a crucially important domain for states, businesses, and individuals, cyberspace still suffers from a regulation deficit. This article takes up one such dangerously underregulated area: cyber warfare and regulation of cyber weapons.
Kalpokienė Julija, Kalpokas Ignas
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Ratification Premium: Hawks, Doves, and Arms Control

open access: yesWorld Politics, 2017
:This article examines the effect of leaders’ foreign policy preferences on their ability to pursue and ratify arms control agreements. Does it take a “Nixon to go to China,” with hawks more effective than doves, when it comes to the domestic politics of
S. Kreps   +2 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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