Results 41 to 50 of about 16,854,833 (379)

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

The Guterres Disarmament Agenda and the Challenge of Constructing a Global Regime for Weapons

Journal for Peace and Nuclear Disarmament, 2020
On 24 May 2018, United Nations Secretary-General António Guterres launched his new “disarmament agenda” in an address at the University of Geneva.
Randy Rydell
doaj   +1 more source

Keys to unblocking multilateral nuclear arms control [PDF]

, 2002
Includes bibliographical references (p. 9.) "July 2002"This article outlines the activities that must be undertaken and the issues that must be addressed in order for multilateral arms control to succeed in the 21st century, given the current US ...
Sands, Amy, Singer, Clifford E.
core  

Mad Momentum Redux? The Rise and Fall of Nuclear Arms Control

Survival: Global Politics and Strategy, 2019
Legacy Cold War-era arms control is collapsing and a nuclear arms race is threatening to return.
A. Arbatov
semanticscholar   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

Irreversibility in Nuclear Arms Control: Lessons from the US-Soviet/Russian Arms Control Process

Journal for Peace and Nuclear Disarmament
The United States and Soviet Union/Russian Federation signed several arms control treaties that mandated reductions in their numbers of deployed nuclear weapons.
Amy F. Woolf
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Deterrence and Arms Control: An Interview with Robert Gallucci

Journal for Peace and Nuclear Disarmament, 2021
Ambassador Robert Gallucci is Distinguished Professor in the Practice of Diplomacy at the Edmund A. Walsh School of Foreign Service, Georgetown University, where he earlier served as the Dean. He led the John D. and Catherine T.
Sharon Squassoni
doaj   +1 more source

Real‐world evidence to support regulatory decision‐making for medicines: Considerations for external control arms

Pharmacoepidemiology and Drug Safety, 2020
Randomized clinical trials (RCTs) are the gold standard in producing clinical evidence of efficacy and safety of medical interventions. More recently, a new paradigm is emerging—specifically within the context of preauthorization regulatory decision ...
M. Burcu, N. Dreyer, J. Franklin, Michael D. Blum, C. Critchlow, E. Perfetto, Wei Zhou   +6 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source