Results 51 to 60 of about 15,875,601 (337)
Russia’s Current Nuclear Modernization and Arms Control
Journal for Peace and Nuclear Disarmament, 2018 Russia’s strategic modernization program suggests that it is determined to continue its reliance on nuclear weapons as a key element of its national security strategy. The US is now also committed to the large-scale modernization of its strategic forces.
Pavel Podvig
semanticscholar +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Arms Control and Delivery Vehicles: Challenges and Ways Forward
Journal for Peace and Nuclear Disarmament, 2022 Nuclear arms control remains a priority for the foreseeable future for many stakeholders, and proposals have emerged to focus on capping nuclear warheads of the main nuclear-weapon states.
Emmanuelle Maitre
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
NUST Journal of International Peace and StabilityCivil-military relations constitute a complex area of international relations through the interaction of military institutions, civil society, and other governmental bureaucracies.
Sardar Jehanzaib Ghalib
doaj +1 more source
No First Use and Credible Deterrence
Journal for Peace and Nuclear Disarmament, 2018 Despite progress in reducing the number of nuclear weapons in the largest arsenals, a number of states are now looking to increase their reliance on nuclear weapons not only for deterrence, but also for coercion or war fighting.
Steve Fetter, Jon Wolfsthal
doaj +1 more source
The COVID-19 infection control arms race
Infection control and hospital epidemiology, 2020 US hospitals are engaged in an infection control arms race. Hospitals, specialties, and professional groups are spurring one another on to adopt progressively more aggressive measures in response to COVID-19 that often exceed federal and international ...
C. Rhee, M. Baker, M. Klompas
semanticscholar +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source