Results 21 to 30 of about 984,623 (303)

Infiltration of Small Arms and Light Weapons into Benue Valley and Its Impact on the Conflict Between Pastoralists and Farmers

open access: yesInternational Studies Journal, 2023
One of the challenges confronting nation states is the proliferation of small arms and light weapons. This problem is more pronounce in developing countries where there are porous borders and weak institutions responsible for border security like ...
Paulina Ada Akpa   +2 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Arms Proliferation and Violent Conflicts in Nigeria: A Study of Ogun State

open access: yesJournal of African Politics
Arms proliferation is a security concern for many countries and has recently been severely experienced in Nigeria. This study, through a descriptive research design, examined arms smuggling and arms proliferation and its attendant effects on violent ...
Moliki Ahmed Olawale   +2 more
doaj   +1 more source

The role of Brazil in multilateral disarmament efforts

open access: yesRevista Brasileira de Política Internacional, 2017
This article examines Brazil’s motivations, objectives, and action in international instances related to nuclear disarmament, non-proliferation, and arms control, particularly the Treaty of Tlatelolco and the Treaty on the Non-proliferation of Nuclear ...
Sérgio de Queiroz Duarte
doaj   +1 more source

ACTA1 is inhibited by PAX3-FOXO1 through RhoA-MKL1-SRF signaling pathway and impairs cell proliferation, migration and tumor growth in Alveolar Rhabdomyosarcoma

open access: yesCell & Bioscience, 2021
Background Alveolar Rhabdomyosarcoma (ARMS) is a pediatric malignant soft tissue tumor with skeletal muscle phenotype. Little work about skeletal muscle proteins in ARMS was reported.
Qiande Hu   +4 more
doaj   +1 more source

LIBYA: ARMS PROLIFERATION AND ARMED GROUPS. THE LIBYAN CONFLICT REVISED

open access: yesConflict Studies Quarterly, 2022
The study critically analyses the effects of the Libyan arms proliferation, with a focus on the Small Arms and Light Weapons (SALW) in the region. It traces the proliferation of arms occasioned by the Civil War in Libya and establishes an empirical link to some of the regional security challenges to the proliferation. Relevant theoretical perspectives,
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The G8: Global arms exporters: Failing to prevent irresponsible arms transfers [PDF]

open access: yes, 2005
The international arms trade lacks effective control. Irresponsible arms transfers continue to fuel armed violence. They contribute to violations of human rights and international humanitarian law and they undermine development.

core   +1 more source

Small Arms and Light Weapons Proliferation and Gun Violence in West Africa Sub-Region

open access: yesInternational Studies Journal, 2022
The unlawful use of small arms, light weapons proliferation and gun violence is a global problem which affects every country. At the global stage, it is well known that far more people are killed in armed conflict through the use of small arms than by ...
Agbegbedia Oghenevwoke Anthony
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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