Results 31 to 40 of about 984,623 (303)

Controlling the circulation of small arms in international law [PDF]

open access: yes, 2013
International humanitarian law (IHL) and international human rights law (IHRL) have shown an influence on the conventional arms control. A series of negotiations to control the trade of small arms, in particular the diplomatic conference on the arms ...
Hasan, Ramadansyah
core  

Is the NPT Still Relevant? – How to Progress the NPT’s Disarmament Provisions

open access: yesJournal for Peace and Nuclear Disarmament, 2019
The Nuclear Non-Proliferation Treaty is the cornerstone of the global non-proliferation regime. However, the question is the NPT still relevant? may suggest that the importance of NPT has been forgotten.
John Carlson
doaj   +1 more source

The Legality of Small Arms Production

open access: yesContemporary Challenges, 2020
Officially, international control of small arms and light weapons (SALW) has made considerable advancements in recent years, most notably in the form of the 2014 Arms Trade Treaty (ATT). Nonetheless, important systemic and structural deficiencies seem to
Nicola Piccini
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Proliferation of Small Arm and Light Weapon AND Insecurity in Northwestern Nigeria: A Review

open access: yesBulletin of "Carol I" National Defense University
This paper critically reviews the proliferation of Small Arms and Light Weapons (SALW) in Northwestern Nigeria, examining their sources, implications, and connections to rising insecurity. Drawing on a wide range of scholarly and institutional literature,
Mubarak Sulaiman JAMIU
doaj   +1 more source

The Threat of a Nuclear- Armed North Korea and the Possibility of Solutions

open access: yesJurnal Hubungan Internasional, 2015
This article tries to describe the threat of North Korea nuclear to regional and international security. North Korea Nuclear Proliferation is open the possibility of an arms race, even nuclear war in the region. Moreover, North Korea technology’s ability
Zain Maulana
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Uncovering the Major Drivers Behind Small Arms and Light Weapons Proliferation in Northwestern Nigeria

open access: yesBulletin of "Carol I" National Defense University
The spread of SALW in Northwestern Nigeria has intensified banditry, communal attacks, kidnapping, and insecurity. Guided by the Jurgen and Muggah theory, this study examines why weapons are acquired and how they circulate across the region. The analysis
Mubarak Sulaiman JAMIU
doaj   +1 more source

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