Results 151 to 160 of about 56,186 (320)

‘Fracture incidence after 3 years of aromatase inhibitor therapy’ [PDF]

, 2014
Michaël R. Laurent, Patrick Neven, Dirk Vanderschueren   +2 more
openalex   +1 more source

Results and Exploratory Biomarker Analyses of a Phase II Study CHANGEABLE: Combination of PD‐1 Inhibitor and Niraparib in GErm‐Line‐mutAted Metastatic Breast Cancer

MedComm, Volume 7, Issue 4, April 2026.
This phase II trial evaluated the efficacy and safety of niraparib combined with HX008 in metastatic breast cancer (MBC) patients with germline DNA damage response (DDR) gene mutations. This chemotherapy‐free regimen demonstrates promising efficacy and a tolerable safety profile in MBC patients with germline DDR mutations, providing a novel therapeutic
Jian Zhang, Yiqun Du, Yanchun Meng, Yizi Jin, Mingxi Lin, Xuchen Shao, Xiaojun Liu, Yuxin Mu, Yun Liu, Zhen Hu   +9 more
wiley   +1 more source

Meta-analysis of four phase III RCTs of tamoxifen, versus 3rd generation aromatase inhibitors as first-line endocrine therapy for HR+ advanced breast cancer [PDF]

, 2018
J.F.R. Robertson, Christine Campbell, Jan Bogaerts, R. Parideans, Jasmine Lichfield   +4 more
openalex   +1 more source

Hypothalamic‐Pituitary‐Testicular Axis Regulation in Men With Type 2 Diabetes

Clinical Endocrinology, EarlyView.
Mathis Grossmann
wiley   +1 more source

Prioritising research on endocrine disruption in the marine environment: a global perspective

Biological Reviews, Volume 101, Issue 2, Page 848-868, April 2026.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto, Angelica Miglioli, Carlie A. LaLone, Lisa Baumann, Alice Baynes, Mélanie Blanc‐Legendre, Ibon Cancio, Xavier Cousin, ZhiChao Dang, Rémi Dumollard, Alex T. Ford, Christopher Green, Taisen Iguchi, Philippa Kearney, Thomas Knigge, Christophe Minier, Tiphaine Monsinjon, Marta S. Monteiro, Joachim Sturve, Haruna Watanabe, Hiroshi Yamamoto, Gerald Ankley, Deborah M. Power, Ioanna Katsiadaki   +23 more
wiley   +1 more source

Low Testosterone in Men With Type 2 Diabetes: The Role of Estrogen Excess and Aromatase Activity

Clinical Endocrinology, Volume 104, Issue 4, Page 362-371, April 2026.
ABSTRACT Objective Low testosterone is common in men with type 2 diabetes and is associated with adverse metabolic outcomes. Our objective was to identify factors associated with low total and calculated free testosterone (CFT) in men with type 2 diabetes, with a focus on relative estrogen excess and subcutaneous adipose aromatase expression.
Nyo Nyo Z. Tun, Dawn E. W. Livingstone, Fraser W. Gibb   +2 more
wiley   +1 more source

Open-label Phase II study of everolimus plus endocrine therapy in postmenopausal women with ER-positive and HER2-negative metastatic breast cancer (Chloe trial)

Open Access Journal of Clinical Trials, 2018
Tatsunori Shimoi,1 Akihiko Shimomura,1 Tadahiko Shien,2 Yukari Uemura,3 Hiroaki Kato,4 Masahiro Kitada,5 Tatsuya Toyama,6 Tomohiko Aihara,7 Hirofumi Mukai8 1Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan ...
Shimoi T, Shimomura A, Shien T, Uemura Y, Kato H, Kitada M, Toyama T, Aihara T, Mukai H   +8 more
doaj  

DRUG LIKENESS SCORING AND STRUCTURE ACTIVITY/PROPERTY RELATIONSHIPS OF 1,2,3-TRIAZOLE DERIVATEVES AS AROMATASE INHIBITOR

, 2018
Mebarka Ouassaf, Salah Belaıdı, Houmam Belaıdı, Zineb Almi   +3 more
openalex   +2 more sources

Multi‐Omics Data Reveal Estrogen‐Driven Dysregulation and Stromal‐Epithelial Signaling Alterations in Endometrial Polyps

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
Single‐cell transcriptomic profiling reveals that endometrial polyps arise from estrogen‐driven disruption of stromal‐epithelial signaling. Stromal cells exhibit enhanced WNT, IGF, and VEGF pathways, promoting epithelial proliferation and vascular remodeling.
Tingwei Chen, Bo Zhang, Zhengli Zhou, Naixue Yang, Ting Liu, Huimei Zhang, Yu Yin, Xiaomei Wu, Xiaozhuo Li, Tao Yu, Xiaodie Wang, Tianqing Li, E. Dong   +12 more
wiley   +1 more source

Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women [PDF]

, 2009
Lorna J. Gibson, David Lawrence, Claire Dawson, Judith M. Bliss   +3 more
openalex   +1 more source