Results 171 to 180 of about 30,153 (204)
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AROMATASE INHIBITORS, THEIR PHARMACOLOGY AND APPLICATION
Journal of Steroid Biochemistry, 1983Summary Aromatase inhibitors, 4-OHA, 4-acetoxy-A and ATD cause competitive inhibition and inactivation of aromatase in vitro . The latter property may account for sustained aromatase inhibition observed in vivo , even though 4-OHA is cleared rapidly from the circulation.
A.M.H. Brodie +4 more
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Bulletin du cancer, 1999
Aromatase inhibitors used in breast cancer, are drugs that inhibit the transformation of androstenedione and testosterone, respectively in estradiol and estrone. Two classes have been described: steroidal inhibitors which act competitively and irreversibly and non steroidal inhibitors which block the P 450 cytochrome. The first one is aminoglutethimide
M L, Feutrie, J, Bonneterre
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Aromatase inhibitors used in breast cancer, are drugs that inhibit the transformation of androstenedione and testosterone, respectively in estradiol and estrone. Two classes have been described: steroidal inhibitors which act competitively and irreversibly and non steroidal inhibitors which block the P 450 cytochrome. The first one is aminoglutethimide
M L, Feutrie, J, Bonneterre
openaire +1 more source
Aromatase inhibitors ? mechanisms of steroidal inhibitors
Breast Cancer Research and Treatment, 1994Inhibition of aromatase has been an attractive approach for examining the roles of estrogen biosynthesis in various physiological or pathological processes. Effective aromatase inhibitors can serve as potential therapeutic agents for controlling estrogen-dependent diseases such as hormone-dependent breast cancer.
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Fracture incidence after 3 years of aromatase inhibitor therapy
Annals of Oncology, 2014Beatrice Bouvard, E Hoppe, M Audran
exaly