Results 151 to 160 of about 665,294 (217)

Computational strategies to address therapeutic resistance in estrogen receptor‐positive breast cancer: A narrative review of molecular docking, molecular dynamics simulations, and emerging therapeutic targets

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Computational drug discovery integrates molecular docking, molecular dynamics simulations, and translational clinical targeting to identify next‐generation therapeutics that overcome endocrine resistance in ER‐positive breast cancer. Combined with multi‐omics, artificial intelligence, and biomarker‐guided precision oncology, these approaches accelerate
Emmanuel Ifeanyi Obeagu, Yaregal Asres
wiley   +1 more source

Aromatase Inhibitor Therapy Is Associated with Distinct Plasma Lipidomic Profiles in Postmenopausal Breast Cancer Patients. [PDF]

Int J Mol Sci
Arsic A, Kvasnicka A, Friedecky D, Ivanovic N, Milosevic M, Vucic V.   +5 more
europepmc   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 396-407, October 2026.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Management Strategies for Aromatase Inhibitor-Associated Musculoskeletal Symptoms and Their Impact on Treatment Persistence in Postmenopausal Breast Cancer: A Single-Center Retrospective Cohort Study. [PDF]

Int J Womens Health
Liang M, Yuan S, Xue Y, Li J, Chen C.
europepmc   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 26-47, October 2026.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source

Adherence to Aromatase Inhibitor Therapy in Breast Cancer: Insights From a Multicenter Italian Study. [PDF]

Breast J
Fabbri MA, Fulvi A, Vergati M, D'Auria G, Vici P, Filomeno L, Arcuri T, Palazzo A, Nelli F, Fiore C, Portarena I, Falbo PT, Rossi R, Alesini D, Sini V, Pace R, Frittelli P, Corsi DC, Palombi L, Pisegna S, Botticelli A, Scagnoli S, Pistillucci G, Giordani E, La Cesa A.   +24 more
europepmc   +1 more source

Concurrent Antidepressant Use and Metastasis Risk Among Women Receiving Tamoxifen for Breast Cancer: A Real‐World Cohort Study

Psycho-Oncology, Volume 35, Issue 10, October 2026.
ABSTRACT Objective Concurrent use of antidepressants, particularly cytochrome P450 2D6 (CYP2D6) inhibitors, may reduce tamoxifen bioactivation and effectiveness. However, the clinical significance of this potential interaction remains inconclusive. This study examined whether concurrent antidepressant use is associated with increased metastasis risk ...
Shaimaa Elshafie, Mohammed Zuber, Ainhoa Gomez‐Lumbreras, Daniel C. Malone, Lorenzo Villa Zapata   +4 more
wiley   +1 more source

Aromatase Inhibitor-Related Alveolar Hemorrhage or ANCA-Associated Vasculitis? [PDF]

Eur J Breast Health
Büyükavcı R.
europepmc   +1 more source

Sonographic Assessment of Prostate Volume, Prostate Dimensions, and Associated Factors Among Adult Men Attending the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross‐Sectional Study

Trends in Urology &Men's Health, Volume 17, Issue 5, October 2026.
ABSTRACT The prostate gland is the only internal organ that continues to enlarge throughout adulthood, and it is an important parameter in the evaluation of benign prostatic enlargement and other prostate disorders. However, data on prostate volume and its associated factors are limited in Ethiopia.
Alemker Molla Yitayew, Bahiru Tenaw, Temesgen Tadesse, Molla Taye   +3 more
wiley   +1 more source

Overall Survival With Palbociclib and Aromatase Inhibitor Versus Aromatase Inhibitor Alone in Older Patients With HR+/HER2- Metastatic Breast Cancer. [PDF]

Cancer Med
Brufsky AM, Sandin R, Stergiopoulos S, Chen C, Karanth S, Li B, Esterberg E, Makari D, Candrilli SD, Goyal RK, Rugo HS.   +10 more
europepmc   +1 more source