Results 171 to 180 of about 56,186 (320)
Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby
Developmental Dynamics, Volume 255, Issue 3, Page 340-361, March 2026.Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe +3 more
wiley +1 more source
Antiestrogen pathway (aromatase inhibitor) [PDF]
Pharmacogenetics and Genomics, 2009 Zeruesenay, Desta +8 more
openaire +2 more sources
Aromatase overexpression and breast hyperplasia, an in vivo model--continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary glands. [PDF]
, 1999 Rajeshwar R. Tekmal +3 more
openalex +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Chamomile contains different bioactive agents such as flavonoids and phytosterols with potential anti‐inflammatory, antioxidant, analgesic, antispasmodic, and antitumor characteristics. According to our findings, animal studies have demonstrated the potential benefits of Chamomile consumption in the treatment of PCOS. In contrast, human studies yielded
Zahra Firoozi +3 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley +1 more source
International Journal of Cancer, Volume 158, Issue 5, Page 1184-1192, 1 March 2026.What's New? The prognostic significance of the presence or absence of human epidermal growth factor receptor 2 (HER2) and estrogen receptor (ER) in breast cancer is well‐established. However, the relationship of HER2 and ER with distant disease recurrence and metastasis location is less well understood.
Damien Kaukonen +4 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 3, March 2026.Letrozole induces neurotoxicity by promoting oxidative stress, inflammation, and apoptotic signaling in the brain. Hesperidin co‐treatment mitigates these effects by restoring redox balance, suppressing pro‐inflammatory cytokines, and normalizing Bax/Bcl‐2–mediated apoptotic pathways, thereby exerting neuroprotective effects.
İdris Ayhan +4 more
wiley +1 more source