Results 171 to 180 of about 180,821 (311)

Are comorbid sleep disorders associated with higher risk for sudden unexpected death in epilepsy? Observations from a Canadian epilepsy clinic

Epilepsia, EarlyView.
Abstract Objective Pooled mortality is nearly three times higher in people with epilepsy (PWE). Approximately 80% of sudden unexpected death in epilepsy (SUDEP) events occur during sleep, and primary sleep disorders are prevalent in the general population and PWE.
Marion Lazaj, Ellen Lee, Tristan Derry, Helen Driver, Gavin P. Winston, Lysa Boissé Lomax, Ana Johnson, Garima Shukla   +7 more
wiley   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

Epilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni, Karine Brochu, Paolo Federico, Walter Hader, Julia W. Y. Kam, Fady Girgis   +5 more
wiley   +1 more source

Precision phenotyping of elevated arousal in posttraumatic stress disorder: implications for personalized GABAergic pharmacotherapy. [PDF]

Front Psychiatry
Vasquez VR, Howlett JR.
europepmc   +1 more source

Arousal modulates valence effects on both early and late stages of affective picture processing in a passive viewing task

, 2014
Valence and arousal are primary dimensions of affective stimuli. An interaction of these two factors on affective processing is largely unknown. In this study, the processing of affective pictures was investigated in an orthogonal valence (positive vs ...
Li, Wanqing, Feng, Chunliang, Gu, Ruolei, Luo, Yi, Tian, Tengxiang, Zhou, Chenglin, Luo, Yue-jia   +6 more
core  

The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI

Epilepsia, EarlyView.
Abstract Objective Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication‐resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized ...
Lucas E. Sainburg, Alexandra Roche, Ghassan S. Makhoul, Baxter P. Rogers, Shawniqua Williams Roberson, Stefano Meletti, Anna E. Vaudano, Catie Chang, Dario J. Englot, Victoria L. Morgan   +9 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Cortical synchrony is reduced in Alzheimer's disease and relates to arousal state. [PDF]

Alzheimers Dement
David MCB, Mallas EJ, Kolanko MA, Del Giovane M, Kurtin DL, Nilforooshan R, Zimmerman KA, Bonet Olivares C, Lally PJ, CR&T Group of UKDRI, Sharp DJ, Malhotra PA, Scott G.   +12 more
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

The ventilatory response to arousal from sleep is elevated in young individuals with post-traumatic stress disorder symptoms. [PDF]

J Clin Sleep Med
Schenker MT, Russell A, Cherian D, Pan Y, Bruce G, Zeng L, Avraam J, J O'Donoghue F, Felmingham KL, Jordan AS.   +9 more
europepmc   +1 more source