Results 51 to 60 of about 1,071,960 (344)

Effect of a Strategy of a Supraglottic Airway Device vs Tracheal Intubation During Out-of-Hospital Cardiac Arrest on Functional Outcome: The AIRWAYS-2 Randomized Clinical Trial

open access: yesJournal of the American Medical Association (JAMA), 2018
Importance The optimal approach to airway management during out-of-hospital cardiac arrest is unknown. Objective To determine whether a supraglottic airway device (SGA) is superior to tracheal intubation (TI) as the initial advanced airway management ...
J. Benger   +17 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Resuscitation Education Science: Educational Strategies to Improve Outcomes From Cardiac Arrest A Scientific Statement From the American Heart Association

open access: yesCirculation, 2018
The formula for survival in resuscitation describes educational efficiency and local implementation as key determinants in survival after cardiac arrest.
A. Cheng   +13 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A Rare Cardiotoxicity: Butane Inhalation

open access: yesJournal of Pediatric Emergency and Intensive Care Medicine, 2018
The number of cases of voluntary inhalation of volatile substances is increasing all over the world and in our country. This is a social health problem that can be encountered in different socioeconomic and cultural levels.
Gamze Gökalp   +6 more
doaj   +1 more source

Arresting Evolution [PDF]

open access: yesTrends in Genetics, 2017
Evolution in the form of selective breeding has long been harnessed as a useful tool by humans. However, rapid evolution can also be a danger to our health and a stumbling block for biotechnology. Unwanted evolution can underlie the emergence of drug and pesticide resistance, cancer, and weeds.
James J, Bull, Jeffrey E, Barrick
openaire   +2 more sources

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

open access: yesGenes & Development, 1994
Cell-cell contact and TGF-beta can arrest the cell cycle in G1. Mv1Lu mink epithelial cells arrested by either mechanism are incapable of assembling active complexes containing the G1 cyclin, cyclin E, and its catalytic subunit, Cdk2.
K. Polyak   +6 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Hindsight bias and the practice of arrests in Poland

open access: yesRuch Prawniczy, Ekonomiczny i Socjologiczny
This comparative study deals with the various forms of arrest in the Polish criminal law system. The authors used the dogmatic-legal and comparative methods, and applied the empirical method in several case studies.
Barbara Janusz-Pohl   +1 more
doaj   +1 more source

The Reform of Law-Enforcement Agencies in Kyiv in Terms of Growth and National Revolutionary Movement in the Post-Reform Period of Second Half 19th— Early 20th Ct. [PDF]

open access: yesStorìnki Istorìï, 2016
The article analysis the reorganization of law-enforcement agencies in Kyiv in the period of reforming of the entire state apparatus of the Russian Empire in the late 19th and early 20th ct.
O. Biliavska
doaj  

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