Results 111 to 120 of about 524,035 (381)

Diabetes and Arrhythmias: Pathophysiology, Mechanisms and Therapeutic Outcomes

Frontiers in Physiology, 2018
The prevalence of diabetes is rapidly increasing and closely associated with cardiovascular morbidity and mortality. While the major cardiovascular complication associated with diabetes is coronary artery disease, it is becoming increasingly apparent ...
Laurel A. Grisanti
semanticscholar   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Mitochondria and arrhythmias

Free Radical Biology and Medicine, 2014
Mitochondria are essential to providing ATP, thereby satisfying the energy demand of the incessant electrical activity and contractile action of cardiac muscle. Emerging evidence indicates that mitochondrial dysfunction can adversely affect cardiac electrical functioning by impairing the intracellular ion homeostasis and membrane excitability through ...
Marcelo G. Bonini, Samuel C. Dudley, Kai-Chien Yang   +2 more
openaire   +4 more sources

Nonischemic Left Ventricular Scar as a Substrate of Life-Threatening Ventricular Arrhythmias and Sudden Cardiac Death in Competitive Athletes

Circulation: Arrhythmia and Electrophysiology, 2016
Background—The clinical profile and arrhythmic outcome of competitive athletes with isolated nonischemic left ventricular (LV) scar as evidenced by contrast-enhanced cardiac magnetic resonance remain to be elucidated.
A. Zorzi, M. Perazzolo Marra, I. Rigato, M. De Lazzari, Angela Susana, A. Niero, K. Pilichou, F. Migliore, S. Rizzo, Benedetta Giorgi, G. De Conti, P. Sarto, L. Serratosa, G. Patrizi, E. De Maria, A. Pelliccia, C. Basso, M. Schiavon, B. Bauce, S. Iliceto, G. Thiene, D. Corrado   +21 more
semanticscholar   +1 more source

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]

, 2009
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S., Robson , Noorzurani, Vicknasingam, B.   +2 more
core  

Biodegradable Medical Implants: Reshaping Future Medical Practice

Advanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia, Yan Liu, Yangkun Xing, Zhewei Shi, Xiaocheng Pang   +4 more
wiley   +1 more source

Hypertension and cardiac arrhythmias: a consensus document from the European Heart Rhythm Association (EHRA) and ESC Council on Hypertension, endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS) and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiologí

Europace, 2017
Hypertension is a common cardiovascular risk factor leading to heart failure (HF), coronary artery disease, stroke, peripheral artery disease and chronic renal insufficiency.
G. Lip, A. Coca, T. Kahan, G. Boriani, A. Manolis, M. Olsen, A. Oto, T. Potpara, J. Steffel, F. Marín, M. J. de Oliveira Figueiredo, G. de Simone, Wendy S. Tzou, C. Chiang, B. Williams, G. Dan, B. Gorenek, L. Fauchier, I. Savelieva, R. Hatala, I. V. Van Gelder, Jana Brguljan-Hitij, S. Erdine, D. Lovic, Young-Hoon Kim, Jorge Salinas-Arce, Michael Field   +26 more
semanticscholar   +1 more source

Andersen-Tawil Syndrome [PDF]

, 2006
Andersen-Tawil syndrome (ATS) is a rare condition consisting of ventricular arrhythmias, periodic paralysis, and dysmorphic features. In 2001, mutations in KCNJ2, which encodes the α subunit of the potassium channel Kir2.1, were identified in patients ...
Fish, Frank A, Kannankeril, Prince J, Smith, Andrew H   +2 more
core   +2 more sources

Non-compaction cardiomyopathy – brief review [PDF]

, 2017
Left ventricular non-compaction cardiomyopathy is a genetic disorder characterized by the presence of two myocardial layers with numerous prominent trabeculations and deep inter-trabecular recesses that communicate with the ventricular cavity.
Berceanu, Mihaela, Constantin, Anca, Donoiu, Ionuț, Istrătoaie, Octavian, Militaru, Constantin, Mirea, Oana, Mănescu, Mirela, Târtea, Georgică Costinel   +7 more
core   +3 more sources

A Novel Theoretical Hypothesis on Comorbidity in the Elderly—The Disease of Sympathetic Overdrive (DSO)

AGING MEDICINE, EarlyView.
A novel hypothesis: The disease of sympathetic overdrive (DSO) as a unifying mechanism for comorbidity in the elderly. ABSTRACT The coexistence of multimorbidity and geriatric syndromes is a big character and role target to manage for the clinic works in older age, but related theories still require innovation and exploration.
Li Jie, Kong Jian, Yu Boxin, Li Hongyang
wiley   +1 more source