Results 31 to 40 of about 353,349 (237)

Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

Frontiers in Physiology, 2023
Background: SGLT2i directly inhibit the cardiac sodium-hydrogen exchanger-1 (NHE1) in isolated ventricular cardiomyocytes (CMs). However, other studies with SGLT2i have yielded conflicting results.
Sha Chen, Sha Chen, Cees A. Schumacher, Cees A. Schumacher, Shirley C. M. Van Amersfoorth, Shirley C. M. Van Amersfoorth, Jan W. T. Fiolet, Jan W. T. Fiolet, Antonius Baartscheer, Antonius Baartscheer, Marieke W. Veldkamp, Marieke W. Veldkamp, Ruben Coronel, Ruben Coronel, Coert J. Zuurbier, Coert J. Zuurbier   +15 more
doaj   +1 more source

Acute echocardiographic effects of sotalol on ventricular systolic function in dogs with ventricular arrhythmias. [PDF]

, 2018
BackgroundSotalol is a commonly used antiarrhythmic drug that may alter ventricular function.ObjectiveTo determine the effect of sotalol on echocardiographic indices of ventricular systolic function in dogs with ventricular arrhythmias.AnimalsThirty-five
Anderson, Baumwart, Chetboul, Cornell, Dukes-McEwan, Hansson, Hoffmann, Hohnloser, Kaye, Mahmarian, Maran, Martin, Meurs, Meurs, Meurs, Meurs, Motskula, Oyama, Palermo, Peralta, Schnelle, Seidler, Singh, Smets, Stephenson, Summerfield, Visser, Visser, Wess, Wess, Zupan   +30 more
core   +2 more sources

LRP6 acts as a scaffold protein in cardiac gap junction assembly

Nature Communications, 2016
LRP6 is known for its role as a Wnt co-receptor essential for the canonical Wnt/β-catenin signaling. Here, Li et al. show that LRP6 exerts a Wnt-independent scaffold function and regulates connexin 43 gap junction formation and coupling of cardiomyocytes
Jun Li, Changming Li, Dandan Liang, Fei Lv, Tianyou Yuan, Erlinda The, Xiue Ma, Yahan Wu, Lixiao Zhen, Duanyang Xie, Shiyi Wang, Yuan Liu, Jian Huang, Jingyi Shi, Yi Liu, Dan Shi, Liang Xu, Li Lin, Luying Peng, Jianmin Cui, Weidong Zhu, Yi-Han Chen   +21 more
doaj   +1 more source

Early detection of biochemically occult autonomous thyroid nodules [PDF]

, 2016
Objective: Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism, but may exist even in the presence of normal TSH.
Brusca, Nunzia, Capriello, Silvia, Cellini, Miriam, Centanni, Marco, Gargano, L., Salvatori, R., Santaguida, MARIA GIULIA, Virili, Camilla   +7 more
core   +1 more source

Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China

Scientific Reports, 2018
To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, China.
Longbing Ren, Yongtao Zheng, Lezhou Wu, Yijun Gu, Yusheng He, Bo Jiang, Jie Zhang, Lijuan Zhang, Jue Li   +8 more
doaj   +1 more source

The ATLAS Randomised Clinical Trial: What do the Superiority Results Mean for Subcutaneous ICD Therapy and Sudden Cardiac Death Prevention as a Whole?

Arrhythmia & Electrophysiology Review, 2022
This review sets out the key evidence comparing subcutaneous ICDs (S-ICDs) and transvenous ICDs and uses it to empower clinical cardiologists and those who implant ICDs to make optimum patient selections for S-ICD use.
Roberto Rordorf
doaj   +1 more source

Radiofrequency Catheter Ablation of Atrioventricular Nodal Reentrant Tachycardia: It Is Not Always As It Is Expected [PDF]

, 2004
Observation of Coincident arrhythmias is not uncommon but the co-existence of idiopathic verapamil sensitive left ventricular tachycardia (ILVT) with other arrhythmias is very rare.
Arya, Arash, Emkanjoo, Zahra, Haghjoo, Majid, Heydari, Alireza, Sadr-Ameli, Mohammad Ali   +4 more
core   +1 more source

A comparative study of early afterdepolarization-mediated fibrillation in two mathematical models for human ventricular cells [PDF]

, 2015
Early afterdepolarizations (EADs), which are abnormal oscillations of the membrane potential at the plateau phase of an action potential, are implicated in the development of cardiac arrhythmias like Torsade de Pointes.
Nayak, Alok Ranjan, Pandit, Rahul, Panfilov, Alexander, Vandersickel, Nele, Zimik, Soling   +4 more
core   +6 more sources

Evaluación de la efectividad de la extracción de electrodos en pacientes con dispositivos electrónicos implantables: el estudio retrospectivo más grande en México

Gaceta Médica de México
Antecedentes: El uso de dispositivos electrónicos implantables cardíacos (CIED) ha aumentado en la última década, incrementando las complicaciones asociadas, siendo las infecciones la principal causa de extracción ...
Ignacio Moreno-Zenteno, Jose A. Manzanarez, Diego Neach-De la Vega, Adela Bazbaz, Carmen A. Sánchez-Contreras, Mario A. Ornelas-Casillas, Sylvia Salmun-Nehmad, Elías Terrazas-Cervantes, Manlio F. Márquez-Murillo, Moisés Levinstein-Jacinto, Jorge R. Gómez-Flores, Jose L. Morales-Velázquez, Santiago Nava   +12 more
doaj   +1 more source

The anatomy of an arrhythmia [PDF]

Journal of Clinical Investigation, 2004
Computer simulations are potentially effective approaches to unraveling the causes of lethal heart rhythm disorders. In this issue of the JCI, Xie et al. have embedded a well-characterized dynamic mechanism for arrhythmia development in an anatomically realistic computer model of the heart.
openaire   +2 more sources