Results 41 to 50 of about 71,558 (258)

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

ECG-based evaluation of ventricular synchrony in left bundle branch area pacing through characterization of the activation sequence

Scientific Reports
Left bundle branch area pacing (LBBAP) overcomes ventricular dyssynchrony induced by conventional right ventricular pacing (RVP). Despite QRS duration (QRSd) being the standard ECG marker for biventricular synchrony, it lacks insights into the ...
Clara Sales-Belles, Ana Mincholé, Jorge Melero-Polo, Mercedes Cabrera-Ramos, Pablo Vadillo-Martín, Isabel Montilla-Padilla, Laura Sorinas-Villanueva, Inés Julián-García, Gualber Vitto Mayo-Carlos, José Ramón Ruiz-Arroyo, Esther Pueyo, Javier Ramos-Maqueda   +11 more
doaj   +1 more source

Evaluación de la efectividad de la extracción de electrodos en pacientes con dispositivos electrónicos implantables: el estudio retrospectivo más grande en México

Gaceta Médica de México
Antecedentes: El uso de dispositivos electrónicos implantables cardíacos (CIED) ha aumentado en la última década, incrementando las complicaciones asociadas, siendo las infecciones la principal causa de extracción ...
Ignacio Moreno-Zenteno, Jose A. Manzanarez, Diego Neach-De la Vega, Adela Bazbaz, Carmen A. Sánchez-Contreras, Mario A. Ornelas-Casillas, Sylvia Salmun-Nehmad, Elías Terrazas-Cervantes, Manlio F. Márquez-Murillo, Moisés Levinstein-Jacinto, Jorge R. Gómez-Flores, Jose L. Morales-Velázquez, Santiago Nava   +12 more
doaj   +1 more source

The ATLAS Randomised Clinical Trial: What do the Superiority Results Mean for Subcutaneous ICD Therapy and Sudden Cardiac Death Prevention as a Whole?

Arrhythmia & Electrophysiology Review, 2022
This review sets out the key evidence comparing subcutaneous ICDs (S-ICDs) and transvenous ICDs and uses it to empower clinical cardiologists and those who implant ICDs to make optimum patient selections for S-ICD use.
Roberto Rordorf
doaj   +1 more source

Evolution of Extravascular Implantable Cardioverter-Defibrillator Therapy for Ventricular Arrhythmias

, 2022
Implantable cardioverter-defibrillators have become an established therapy for the prevention of sudden cardiac death due to life-threatening ventricular arrhythmias in the last decades.
Römers, Hans, van Dijk, Vincent, Boersma, Lucas   +2 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Arrhythmias and pacing [PDF]

European Heart Journal, 2015
Arrhythmias remain a frequent cause of morbidity and mortality in cardiovascular (CV) patients, and thus an important issue for practising cardiologists. Therefore, the European Society of Cardiology has published guidelines on cardiac pacing and resynchronization therapy1 and on atrial fibrillation,2 syncope,3 and ventricular arrhythmias,4 and ...
openaire   +3 more sources

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Perioperative arrhythmias

Middle Black Sea Journal of Health Science, 2017
Arrhythmias are the most commonly encountered cardiovascular complicationsduring anesthesia administration. Perioperative arrhythmias disrupt thehemodynamic state of the patients and are known to cause increases in mortalityand morbidity. Anesthetic agents and methods affect cardiac conduction andcause arrhythmia.
Altınbaş, Ali, Taş, Nilay, Bektaş, Osman   +2 more
openaire   +3 more sources