Results 41 to 50 of about 228,705 (316)

Evolution of Extravascular Implantable Cardioverter-Defibrillator Therapy for Ventricular Arrhythmias

, 2022
Implantable cardioverter-defibrillators have become an established therapy for the prevention of sudden cardiac death due to life-threatening ventricular arrhythmias in the last decades.
Römers, Hans, van Dijk, Vincent, Boersma, Lucas   +2 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Role of the Purkinje system in heritable arrhythmias

, 2019
Much has been written about arrhythmias in structurally normal hearts. In this review, we focus on rapid ventricular arrhythmias that occur in hearts having a pathogenic genetic variant that has been found in families in which arrhythmias occur.
Wilde, Arthur A.M., Boyden, Penelope A., Garan, Hasan   +2 more
core   +1 more source

How Cardiac Embryology Translates into Clinical Arrhythmias

, 2021
The electrophysiological signatures of the myocardium in cardiac structures, such as the atrioventricular node, pulmonary veins or the right ventricular outflow tract, are established during development by the spatial and temporal expression of ...
Monique R. M. Jongbloed, Boukens, Bastiaan J., Michiel Blok, Rivaud, Mathilde R., Jongbloed, Monique R. M., Mathilde R. Rivaud, Blok, Michiel, Bastiaan J. Boukens   +7 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Evaluación de la efectividad de la extracción de electrodos en pacientes con dispositivos electrónicos implantables: el estudio retrospectivo más grande en México

Gaceta Médica de México
Antecedentes: El uso de dispositivos electrónicos implantables cardíacos (CIED) ha aumentado en la última década, incrementando las complicaciones asociadas, siendo las infecciones la principal causa de extracción ...
Ignacio Moreno-Zenteno, Jose A. Manzanarez, Diego Neach-De la Vega, Adela Bazbaz, Carmen A. Sánchez-Contreras, Mario A. Ornelas-Casillas, Sylvia Salmun-Nehmad, Elías Terrazas-Cervantes, Manlio F. Márquez-Murillo, Moisés Levinstein-Jacinto, Jorge R. Gómez-Flores, Jose L. Morales-Velázquez, Santiago Nava   +12 more
doaj   +1 more source

The ATLAS Randomised Clinical Trial: What do the Superiority Results Mean for Subcutaneous ICD Therapy and Sudden Cardiac Death Prevention as a Whole?

Arrhythmia & Electrophysiology Review, 2022
This review sets out the key evidence comparing subcutaneous ICDs (S-ICDs) and transvenous ICDs and uses it to empower clinical cardiologists and those who implant ICDs to make optimum patient selections for S-ICD use.
Roberto Rordorf
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

ECG-based evaluation of ventricular synchrony in left bundle branch area pacing through characterization of the activation sequence

Scientific Reports
Left bundle branch area pacing (LBBAP) overcomes ventricular dyssynchrony induced by conventional right ventricular pacing (RVP). Despite QRS duration (QRSd) being the standard ECG marker for biventricular synchrony, it lacks insights into the ...
Clara Sales-Belles, Ana Mincholé, Jorge Melero-Polo, Mercedes Cabrera-Ramos, Pablo Vadillo-Martín, Isabel Montilla-Padilla, Laura Sorinas-Villanueva, Inés Julián-García, Gualber Vitto Mayo-Carlos, José Ramón Ruiz-Arroyo, Esther Pueyo, Javier Ramos-Maqueda   +11 more
doaj   +1 more source

Effectiveness and safety of mexiletine in patients at risk for (recurrent) ventricular arrhythmias: a systematic review

, 2022
AIMS: While mexiletine has been used for over 40 years for prevention of (recurrent) ventricular arrhythmias and for myotonia, patient access has recently been critically endangered.
Stolwijk, Nina, Jacobs, Bart A W, van Dussen, Laura, Wilde, Arthur A M, van den Berg, Sibren, Rosenberg, Noa, Hollak, Carla E M, van der Ree, Martijn H, van der Wel, Vincent, Postema, Pieter G   +9 more
core   +1 more source